BDBM556684 3-[(4-Chloro-5-methyl-2-propan-2-ylphenoxy)methyl]-1H-indazole::US11352330, Example D2

SMILES Cc1cc(c(cc1Cl)C(C)C)OCc2c3ccccc3[nH]n2

InChI Key InChIKey=HBOLFNCNYFBJGH-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 556684   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 556684BDBM556684(3-[(4-Chloro-5-methyl-2-propan-2-ylphenoxy)methyl]...)
Affinity DataIC50: 14nMAssay Description:Assay working solutions were made as follows:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)