BDBM557944 US11365191, Example 47::US11365191, Example 49

SMILES CC(=O)Nc1ccc(-c2nc3c(s2)CN(CC#N)CC3)c(Nc2cc(C)nc(C(C)(F)F)n2)c1

InChI Key InChIKey=DLHSMWWTHCLUMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 557944   

LigandChemical structure of BindingDB Monomer ID 557944BDBM557944(N-(5-(5-(cyanomethyl)-4,5,6,7-tetrahydrothiazolo[5...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2026
Entry Details US Patent