BDBM563497 (2S)-2-amino-3-(4-(2- amino-6-((R)-2,2,2- trifluoro-1-(3'- methoxy-[1,1'- biphenyl]-4- yl)ethoxy)pyrimidine-4- yl)cyclohex-3-ene-1- yl)propionic acid hydrochloride::US11407763, Example 34::US11407763, Example 58

SMILES COc1cccc(c1)-c1ccc(cc1)[C@@H](Oc1cc(nc(N)n1)C1=CCC(C[C@H](N)C(O)=O)CC1)C(F)(F)F

InChI Key InChIKey=LIUGZGVJFLUDLM-XVWZFPJNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563497   

TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563497((2S)-2-amino-3-(4-(2- amino-6-((R)-2,2,2- triflu...)
Affinity DataIC50:  204nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563497((2S)-2-amino-3-(4-(2- amino-6-((R)-2,2,2- triflu...)
Affinity DataIC50:  281nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent