BDBM575683 US11464802, Compound 47
SMILES C[C@H]1CCCN(Cc2cc3C(=O)N(Cc3c(c2)C(F)(F)F)c2cc(cc(Cl)n2)C2(Cc3nncn3C)COC2)C1
InChI Key InChIKey=IHEZGLKLCGKELM-KRWDZBQOSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 575683
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics
US Patent
Nurix Therapeutics
US Patent
Affinity DataIC50: 52.5nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair