BDBM58242 3-(4-methoxyphenyl)-5-phenyl-2-(trifluoromethyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one::3-(4-methoxyphenyl)-5-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one::CHEMBL522297::MLS000850070::SMR000456088::cid_2810122

SMILES COc1ccc(cc1)-c1c([nH]n2c1nc(cc2=O)-c1ccccc1)C(F)(F)F

InChI Key InChIKey=UVPIEFKZXQPGBJ-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 58242   

TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM58242(3-(4-methoxyphenyl)-5-phenyl-2-(trifluoromethyl)-1...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM58242(3-(4-methoxyphenyl)-5-phenyl-2-(trifluoromethyl)-1...)
Affinity DataIC50:  2.02E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor-binding protein(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM58242(3-(4-methoxyphenyl)-5-phenyl-2-(trifluoromethyl)-1...)
Affinity DataIC50:  1.57E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCorticotropin-releasing factor-binding protein(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM58242(3-(4-methoxyphenyl)-5-phenyl-2-(trifluoromethyl)-1...)
Affinity DataEC50: >5.30E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay