BDBM585306 5-(4-phenylpiperazin-1-yl)-6- propylpyrimidine-2,4-diamine::US11530198, Example 49

SMILES CCCc1nc(N)nc(N)c1N1CCN(CC1)c1ccccc1

InChI Key InChIKey=NVJSDHWZOFXFSJ-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 585306   

TargetDihydrofolate reductase(Human)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM585306(5-(4-phenylpiperazin-1-yl)-6- propylpyrimidine-2,4...)
Affinity DataIC50:  9.12E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent


TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium Falciparum)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM585306(5-(4-phenylpiperazin-1-yl)-6- propylpyrimidine-2,4...)
Affinity DataIC50:  14.1nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent


TargetDihydrofolate reductase(Human)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM585306(5-(4-phenylpiperazin-1-yl)-6- propylpyrimidine-2,4...)
Affinity DataIC50:  1.12E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent


TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM585306(5-(4-phenylpiperazin-1-yl)-6- propylpyrimidine-2,4...)
Affinity DataIC50:  18.2nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
PDB3D3D Structure (crystal)