BDBM589158 US11548900, Example 129
SMILES CN(C\C=C\C(=O)N1CCOc2c1ccc1ncnc(Nc3ccc(Oc4ccn5ncnc5c4)c(Cl)c3)c21)C1CCC1
InChI Key InChIKey=JWSPAXKLFBECIB-ZZXKWVIFSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 589158
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing Scitech-Mq Pharmaceuticals
US Patent
Beijing Scitech-Mq Pharmaceuticals
US Patent
Affinity DataIC50: 275nMAssay Description:The assay for the inhibition of EGFR and HER2 kinase activity by small molecular compounds was carried out using the method as follows:1) Dilution of...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Beijing Scitech-Mq Pharmaceuticals
US Patent
Beijing Scitech-Mq Pharmaceuticals
US Patent
Affinity DataIC50: <50nMAssay Description:The assay for the inhibition of EGFR and HER2 kinase activity by small molecular compounds was carried out using the method as follows:1) Dilution of...More data for this Ligand-Target Pair