BDBM590751 US11564920, Example 36

SMILES COc1cncc(O[C@H]2C[C@H](N)[C@H]3C[C@@H]23)c1-c1cc(Nc2cnc(cn2)C#N)n[nH]1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 590751   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sumitomo Pharma

US Patent
LigandPNGBDBM590751(US11564920, Example 36)
Affinity DataIC50:  2.20E+4nMAssay Description:The test compounds were added to cultured hERG (human Ether-a-go-go Related Gene) gene stably expressing CHO cell line cells to achieve 0.27 to 100 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Sumitomo Pharma

US Patent
LigandPNGBDBM590751(US11564920, Example 36)
Affinity DataIC50:  0.730nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHK1tide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent