BDBM592044 US11566007, Example A724
SMILES CO[C@@H](C)c1ncccc1-c1c2CC(C)(C)COC(=O)[C@@H]3CCCN(N3)C(=O)[C@H](Cc3cccc(c3)-c3ccc(n1CC(F)(F)F)c2n3)NC(=O)[C@@H](COC1CN(C1)C(=O)C#CC(C)(C)N(C)C)C(C)C
InChI Key InChIKey=LIHVAMZZZOPCNV-TVULLFADSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 592044
Affinity DataIC50: >1.00E+4nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair