BDBM597689 US11603377, Compound 10

SMILES COC1C(=O)C(C)CC/C=C/C=C/C=C(\C)[C@H](NS(=O)(=O)CCO)C[C@H]2CC[C@H](C)[C@](O)(O2)C(=O)C(=O)N(C)C(C)C(=O)OC([C@H](C)C[C@@H]2CC[C@@H](OC3CC3)[C@H](OC)C2)CC(=O)C(C)/C=C(\C)C1O

InChI Key InChIKey=QZEZGMMJVAFAQK-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 597689   

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Aeovian Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 597689BDBM597689(US11603377, Compound 10)
Affinity DataKd:  0.650nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP5(Human)
Aeovian Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 597689BDBM597689(US11603377, Compound 10)
Affinity DataKd:  55nMAssay Description:Biotinylated avi-FKBP51 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP5(Human)
Aeovian Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 597689BDBM597689(US11603377, Compound 10)
Affinity DataKd:  550nMAssay Description:Biotinylated avi-FKBP51 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Aeovian Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 597689BDBM597689(US11603377, Compound 10)
Affinity DataKd:  550nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent