BDBM605384 US11667652, Example 178

SMILES CCn1cc(cn1)C(=O)N[S@@]1(=O)=NC(=O)c2ccc3OC[C@@]4(CN(C[C@@H]5CC[C@H]5[C@@H](OC)\C=C\C[C@H](C)C1)c3c2)SCCc1cc(Cl)ccc41

InChI Key InChIKey=VGUQCGOZPHLEPP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 605384   

TargetBcl-2-like protein 11 [51-76]/Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327](Human)
Gilead Sciences

US Patent

LigandBDBM605384(US11667652, Example 178)Copy SMILESCopy InChI

Affinity DataIC50: 0.0500nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/9/2023
Entry Details
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