BDBM606220 US11685719, Example 8A::US11685719, Example 8B

SMILES Cc1cnc(cc1-n1c(C)cc(OCc2ncc(F)cc2F)c(Cl)c1=O)-n1cccc(C2CCOCC2)c1=O

InChI Key InChIKey=XBYXPZQYVBMFAI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 606220   

TargetMitogen-activated protein kinase 14/1(Homo sapiens (Human))
Xinthera

US Patent
LigandPNGBDBM606220(US11685719, Example 8A | US11685719, Example 8B)
Affinity DataIC50:  0.794nMAssay Description:A typical assay was conducted in 20 μL volume including 60 μM active p38α (Carna, cat #04-152), 10 μM ATP, 1 μM FITC-HSP27 p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM606220(US11685719, Example 8A | US11685719, Example 8B)
Affinity DataIC50: >3.16E+5nMAssay Description:A typical assay was conducted in 20 μL volume including 60 μM active p38α (Carna, cat #04-152), 10 μM ATP, 1 μM FITC-HSP27 p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14/1(Homo sapiens (Human))
Xinthera

US Patent
LigandPNGBDBM606220(US11685719, Example 8A | US11685719, Example 8B)
Affinity DataIC50: >1.00E+3nMAssay Description:A typical assay was conducted in 20 μL volume including 60 μM active p38α (Carna, cat #04-152), 10 μM ATP, 1 μM FITC-HSP27 p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM606220(US11685719, Example 8A | US11685719, Example 8B)
Affinity DataIC50:  2.51E+3nMAssay Description:A typical assay was conducted in 20 μL volume including 60 μM active p38α (Carna, cat #04-152), 10 μM ATP, 1 μM FITC-HSP27 p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent