BDBM606232 US11685719, Example 14A::US11685719, Example 14C
SMILES Cc1cnc(cc1-n1c(C)cc(OCc2ncc(F)cc2F)c(Cl)c1=O)-n1cccc(c1=O)[C@](C)(O)C1CC1
InChI Key InChIKey=FIUUNLIXVYHRAD-MUUNZHRXSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 606232
Affinity DataIC50: 1.58nMAssay Description:A typical assay was conducted in 20 μL volume including 60 μM active p38α (Carna, cat #04-152), 10 μM ATP, 1 μM FITC-HSP27 p...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14/MAP kinase-activated protein kinase 5(Human)
Xinthera
US Patent
Xinthera
US Patent
Affinity DataIC50: >3.16E+5nMAssay Description:A typical assay was conducted in 20 μL volume including 60 μM active p38α (Carna, cat #04-152), 10 μM ATP, 1 μM FITC-HSP27 p...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:A typical assay was conducted in 20 μL volume including 60 μM active p38α (Carna, cat #04-152), 10 μM ATP, 1 μM FITC-HSP27 p...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14/MAP kinase-activated protein kinase 5(Human)
Xinthera
US Patent
Xinthera
US Patent
Affinity DataIC50: 3.16E+3nMAssay Description:A typical assay was conducted in 20 μL volume including 60 μM active p38α (Carna, cat #04-152), 10 μM ATP, 1 μM FITC-HSP27 p...More data for this Ligand-Target Pair