BDBM610011 US11708367, Compound 119::tert-butyl (2R)-2-[[[4-[4- [[1-[(4-fluoro- phenyl)carbamoyl]cyclo- propane- carbonyl]amino]phenoxy]-7- methoxyquinazoline-6- carbonyl]amino]methyl]pyr- rolidine-1-carboxylate
SMILES COc1cc2ncnc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1C(=O)NC[C@H]1CCCN1C(=O)OC(C)(C)C
InChI Key InChIKey=JTNXTIPDQKHRDT-RUZDIDTESA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 610011
Affinity DataIC50: 55nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair