BDBM645106 US20240010684, Ex. No 83
SMILES CC[C@H](C)[C@@H]1NC(=O)NC(=O)CCCCNC(=O)CC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@H]2NC(=O)[C@@H](NC(=O)[C@@H]3C[C@@H]4CCCC[C@@H]4N3C(=O)[C@@H]3CCCN3C(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CSSC2(C)C)NC1=O)[C@@H](C)CC)[C@@H](C)CC)C(N)=O
InChI Key InChIKey=VSMKIDLKRDACGG-LWVGJPDLSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 645106
Affinity DataIC50: 91nMAssay Description:Recombinant human MASP2 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Recombinant human MASP1 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM...More data for this Ligand-Target Pair