BDBM647674 (S)-4-(2-(3-fluorobicyclo[1.1.1]pentan- 1-yl)-3-oxo-2,5,6,7-tetrahydro-3H- pyrrolo[2,1-c][1,2,4]triazol-5- yl)benzonitrile::US20240025912, Compound 1-67

SMILES FC12CC(C1)(C2)n1nc2CC[C@@H](c3ccc(cc3)C#N)n2c1=O

InChI Key InChIKey=RCMCKPBKRPPILN-IGEOTXOUSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647674   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM647674((S)-4-(2-(3-fluorobicyclo[1.1.1]pentan- 1-yl)-3-ox...)
Affinity DataEC50:  279nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent