BDBM647678 3-((5S,7R)-5-(3,5-difluorophenyl)-7- methyl-3-oxo-6,7-dihydro-3H- pyrrolo[2,1-c][1,2,4]triazol-2(5H)- yl)bicyclo[1.1.1]pentane-1-carbonitrile::US20240025912, Compound 1-69

SMILES C[C@@H]1C[C@@H](c2cc(F)cc(F)c2)n2c1nn(c2=O)C12CC(C1)(C2)C#N

InChI Key InChIKey=MYVDDALAIFOLRD-GYUNHILPSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647678   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM647678(3-((5S,7R)-5-(3,5-difluorophenyl)-7- methyl-3-oxo-...)
Affinity DataEC50:  263nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent