BDBM649683 (R)-1-((1-(3-((3′-((2-chloro-4-(((R)-3-hydroxypyrrolidin-1-yl)methyl)-5-methoxy phenoxy)methyl)-2,2′-dimethyl-[1,1′-biphenyl]-3-yl)oxy)propyl)-1H-1,2,3-triazol-4-yl)methyl)pyrrolidin-3-ol::US20240043392, Compound II-11

SMILES COc1cc(OCc2cccc(c2C)-c2cccc(OCCCn3cc(CN4CC[C@@H](O)C4)nn3)c2C)c(Cl)cc1CN1CC[C@@H](O)C1

InChI Key InChIKey=PVLIVBAIKXASBW-FIRIVFDPSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 649683   

TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Xi'An Xinton Pharmaceutcal Research Co.

US Patent
LigandPNGBDBM649683((R)-1-((1-(3-((3′-((2-chloro-4-(((R)-3-hydro...)
Affinity DataKd:  50nMAssay Description:The test compound was dissolved in DMSO to make a stock solution with a final concentration of 10 mM, then diluted to 1× with 1.05× PBS-P+, and then ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Xi'An Xinton Pharmaceutcal Research Co.

US Patent
LigandPNGBDBM649683((R)-1-((1-(3-((3′-((2-chloro-4-(((R)-3-hydro...)
Affinity DataIC50:  55nMAssay Description:A negative control, a positive control and drug administration groups were set up, with two duplicate wells in each group. For the positive control g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent