BDBM654396 5-[3-(4-fluorophenyl)-1,2,4-oxadiazol- 5-yl]-1-propyl-1H-1,2,3- benzotriazole::US11912693, Compound 5

SMILES CCCn1nnc2cc(ccc12)-c1nc(no1)-c1ccc(F)cc1

InChI Key InChIKey=BYOOKZWNDCCQJN-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 654396   

TargetSphingosine 1-phosphate receptor 1(Human)
Trevena

US Patent
LigandChemical structure of BindingDB Monomer ID 654396BDBM654396(US11912693, Compound 5 | 5-[3-(4-fluorophenyl)-1,2...)
Affinity DataEC50: >316nMAssay Description:Agonist-promoted G-protein responses were determined by measuring changes in intracellular cAMP using the HTRF cAMP HiRange kit (CisBio, Cat #: 62AM6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Trevena

US Patent
LigandChemical structure of BindingDB Monomer ID 654396BDBM654396(US11912693, Compound 5 | 5-[3-(4-fluorophenyl)-1,2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist-promoted β-arrestin2 recruitment to the sphingosine-1-phosphate 1 receptor was determined using the β-arrestin PathHunter ) Detecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent