BDBM6753 1,7-Annulated indolocarbazole deriv. 13Cf::24-(hydroxymethyl)-1,15-diazaheptacyclo[17.7.1.0^{2,18}.0^{3,12}.0^{6,11}.0^{13,17}.0^{23,27}]heptacosa-2(18),3(12),4,6(11),7,9,13(17),19(27),20,22-decaene-14,16-dione

SMILES OCC1CCn2c3c1cccc3c1c3C(=O)NC(=O)c3c3c(ccc4ccccc34)c21

InChI Key InChIKey=PDUUZVOLPGEGDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6753   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM6753(1,7-Annulated indolocarbazole deriv. 13Cf | 24-(hy...)
Affinity DataIC50:  210nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed