BDBM7773 3-{[(2,2-Dioxido-1,3-dihydro-2-benzothien-5-yl)amino]-methylene}-5-(1,3-oxazol-5-yl)-1,3-dihydro-2H-indol-2-one::5-({[(3Z)-5-(1,3-oxazol-5-yl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}amino)-1,3-dihydro-2-benzothiophene-2,2-dione::Oxindole-Based Inhibitor 109

SMILES O=C1Nc2ccc(cc2C1C=Nc1ccc2CS(=O)(=O)Cc2c1)-c1cnco1

InChI Key InChIKey=SJEPMZVFPSMGMK-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7773   

TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7773(3-{[(2,2-Dioxido-1,3-dihydro-2-benzothien-5-yl)ami...)
Affinity DataIC50:  8.90nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7773(3-{[(2,2-Dioxido-1,3-dihydro-2-benzothien-5-yl)ami...)
Affinity DataIC50:  19nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed