BDBM81767 15-28-Somatostatin-28::CAS_38916-34-6::CB6417646::Somatostatin-14

SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O

InChI Key InChIKey=NHXLMOGPVYXJNR-UHFFFAOYSA-N

Data  109 KI  26 IC50  5 Kd  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 144 hits for monomerid = 81767   

TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.00160nMAssay Description:Displacement of [125I]-somatostatin from human SSTR2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Rat)
University of Cambridge

Curated by PDSP Ki Database
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0410nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0490nMAssay Description:Inhibition of human sst2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataEC50:  0.0650nMAssay Description:Effective concentration on human somatostatin receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Rat)
University of Cambridge

Curated by PDSP Ki Database
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0680nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0680nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Mouse)
Sandoz Pharma

Curated by PDSP Ki Database
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Rat)
Tulane University

Curated by PDSP Ki Database
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2012
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataIC50: 0.0740nMAssay Description:Displacement of [125I]Tyr11-somatostatin-14 from somatostatin receptor in mouse AtT20 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Mouse)
Sandoz Pharma

Curated by PDSP Ki Database
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2012
Entry Details
PubMed
TargetSomatostatin receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataIC50: 0.0800nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor hSSTR4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Mouse)
Sandoz Pharma

Curated by PDSP Ki Database
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataIC50: 0.0800nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor mSSTR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Mouse)
University of Chicago

Curated by PDSP Ki Database
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0830nMAssay Description:Inhibitory constant against human sst2 receptor at a dose of 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKd:  0.0871nMAssay Description:Binding assay at human somatostatin receptor 2 (hsst2) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0900nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0900nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0900nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0900nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0900nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Sandoz Pharma

Curated by PDSP Ki Database
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataEC50:  0.100nMAssay Description:Inhibition of forskolin-induced cAMP accumulation in CHO-K1 cells expressing human sst2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Sandoz Pharma

Curated by PDSP Ki Database
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2012
Entry Details
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Rat)
Tulane University

Curated by PDSP Ki Database
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Sandoz Pharma

Curated by PDSP Ki Database
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.130nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.130nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.130nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.140nMAssay Description:Inhibition of human sst3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.140nMAssay Description:Inhibition of human sst5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.150nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.150nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataEC50:  0.190nMAssay Description:Inhibition of forskolin-induced cAMP accumulation in CHO-K1 cells expressing human sst5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.190nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity towards human Somatostatin receptor type 2 (sst2) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataIC50: 0.200nMAssay Description:Compound was tested for its potency to displace 3-[125I]- - Tyr11-SRIF-14 from somatostatin receptor on membranes of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetSomatostatin receptor type 5(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.210nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.210nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKd:  0.214nMAssay Description:Binding assay at human somatostatin receptor 3 (hsst3) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
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