BDBM81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-)

SMILES CC(C)C[C@H]1C(=O)N2CCC[C@H]2[C@]3(N1C(=O)[C@](O3)(C(C)C)NC(=O)[C@H]4CN([C@@H]5Cc6c7c(cccc7[nH]c6Br)C5=C4)C)O

InChI Key InChIKey=OZVBMTJYIDMWIL-UHFFFAOYSA-N

Data  68 KI  8 IC50  4 Kd  2 EC50

PDB links: 4 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 82 hits for monomerid = 81993   

TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  0.620nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
1/3/2012
Entry Details
Copy BDB DOIPubMedPDB3D Structure (crystal)
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TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  0.620nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/17/2024
Entry Details
Copy BDB DOIPubMedPDB3D Structure (crystal)
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TargetD(2) dopamine receptor(Mouse)
Medical Research Service

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  0.690nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
11/21/2011
Entry Details
Copy BDB DOIPubMedPDB3D Structure (crystal)
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TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  0.800nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
11/23/2011
Entry Details
Copy BDB DOIPubMedPDB3D Structure (crystal)
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TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  0.800nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
11/23/2011
Entry Details
Copy BDB DOIPubMedPDB3D Structure (crystal)
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TargetAlpha-1D adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  1.12nMMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
5/13/2012
Entry Details Article
Copy BDB DOIPubMed
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TargetAlpha-1B adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  1.38nMMore data for this Ligand-Target Pair

Target InfoUniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
5/13/2012
Entry Details Article
Copy BDB DOIPubMed
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TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  2nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/3/2012
Entry Details Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
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TargetD(3) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  2.10nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
1/3/2012
Entry Details
Copy BDB DOIPubMed
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TargetD(2) dopamine receptor(Bovine)
TBA

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  2.5nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOIPubMedPDB3D Structure (crystal)
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TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKd:  4nMAssay Description:In vitro affinity at mutant D2 receptor (S197A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
11/15/2012
Entry Details Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
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TargetAlpha-1A adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  4.17nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
5/13/2012
Entry Details Article
Copy BDB DOIPubMed
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TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  5.01nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
5/13/2012
Entry Details Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
Copy reaction URL

TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  5.30nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
11/18/2011
Entry Details Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
Copy reaction URL

TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  5.30nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
11/18/2011
Entry Details Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
Copy reaction URL

TargetD(3) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  6.76nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
5/13/2012
Entry Details Article
Copy BDB DOIPubMed
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TargetD(3) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  7.10nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/28/2012
Entry Details
Copy BDB DOIPubMed
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TargetD(3) dopamine receptor(Rat)
U. 109

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  7.40nMMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
11/18/2011
Entry Details Article
Copy BDB DOIPubMed
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TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKd:  8nMAssay Description:In vitro affinity at wild type Dopamine receptor D2 on C6 (glioma) cell membranes.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
11/15/2012
Entry Details Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
Copy reaction URL

TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKd:  8nMAssay Description:In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
11/15/2012
Entry Details Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
Copy reaction URL

TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  8.20nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/28/2012
Entry Details
Copy BDB DOIPubMedPDB3D Structure (crystal)
Copy reaction URL

TargetAlpha-1A adrenergic receptor(Rat)
TBA

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  9nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  10nMAssay Description:Binding affinity towards Dopamine receptor D2 by displacement of [3H]U-86170.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
Copy reaction URL

Target5-hydroxytryptamine receptor 7(Rat)
National Institute of Neurological Disorders and Stroke

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  10.7nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/9/2012
Entry Details
Copy BDB DOIPubMed
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Target5-hydroxytryptamine receptor 7(Rat)
National Institute of Neurological Disorders and Stroke

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  10.7nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/30/2011
Entry Details Article
Copy BDB DOIPubMed
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Target5-hydroxytryptamine receptor 1D(Human)
Institut De Recherches Servier

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  10.7nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
5/13/2012
Entry Details Article
Copy BDB DOIPubMed
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TargetAlpha-2A adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  11.0nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
5/13/2012
Entry Details Article
Copy BDB DOIPubMed
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TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  12.6nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
11/18/2011
Entry Details Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
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Target5-hydroxytryptamine receptor 1A(Human)
Institut De Recherches Servier

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  12.9nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
5/13/2012
Entry Details Article
Copy BDB DOIPubMed
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TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  14.8nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
5/13/2012
Entry Details Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
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TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  15nMAssay Description:Displacement of [125]iodosulpride from human recombinant dopamine D2L receptor expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/11/2015
Entry Details Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
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TargetAlpha-1A adrenergic receptor(Rat)
TBA

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  16nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOIPubMed
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TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKd:  17nMAssay Description:In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
11/15/2012
Entry Details Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
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TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  19nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/2/2012
Entry Details Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
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Target5-hydroxytryptamine receptor 1A(Human)
Institut De Recherches Servier

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  24nMAssay Description:Binding affinity towards Serotonin 5-hydroxytryptamine 1A receptor by displacement of [3H]-(+)-8-OH-DPAT.More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
Copy BDB DOIPubMed
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Target5-hydroxytryptamine receptor 1A(Human)
Institut De Recherches Servier

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  25nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/28/2012
Entry Details
Copy BDB DOIPubMed
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TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rat)
TBA

Curated by ChEMBL

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataIC50: 28nMAssay Description:Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/10/2018
Entry Details Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
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TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rat)
TBA

Curated by ChEMBL

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataIC50: 28nMAssay Description:In vitro affinity for dopamine receptor by displacement of [3H]- apomorphine in rat striatal membranesMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/7/2018
Entry Details Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
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TargetAlpha-2C adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  28.2nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
5/13/2012
Entry Details Article
Copy BDB DOIPubMed
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Target5-hydroxytryptamine receptor 6(Human)
University of Washington

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  33nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/20/2012
Entry Details Article
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TargetAlpha-2B adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  34.7nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
5/13/2012
Entry Details Article
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Target5-hydroxytryptamine receptor 7(Rat)
National Institute of Neurological Disorders and Stroke

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  48.8nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/9/2012
Entry Details
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Target5-hydroxytryptamine receptor 7(Rat)
National Institute of Neurological Disorders and Stroke

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  49.0nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/30/2011
Entry Details Article
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TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  54nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
11/9/2011
Entry Details
Copy BDB DOIPubMedPDB3D Structure (crystal)
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Target5-hydroxytryptamine receptor 2B(Human)
Institut De Recherches Servier

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  56.2nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
5/13/2012
Entry Details Article
Copy BDB DOIPubMed
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TargetAlpha-2A adrenergic receptor [16-465](Rat)
Institut De Recherches Servier

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  67.6nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
5/13/2012
Entry Details Article
Copy BDB DOIPubMed
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TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  68nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/25/2012
Entry Details Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
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TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  83nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
11/9/2011
Entry Details
Copy BDB DOIPubMedPDB3D Structure (crystal)
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TargetD(3) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  87nMAssay Description:Binding affinity towards Dopamine receptor D3 by displacement of [3H](+)-7-OH-DPAT.More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
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Target5-hydroxytryptamine receptor 2A(Human)
Institut De Recherches Servier

Curated by PDSP K_i Database

LigandBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)Copy SMILESCopy InChI

Affinity DataKi:  107nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidPDBSimilars

In Depth
Date in BDB:
5/13/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL