BDBM8798 CHEMBL47787::Pyrazolo[3,4-d]pyrimidine 6::benzyl N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohexyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl}-2-methoxyphenyl)carbamate
SMILES COc1cc(ccc1NC(=O)OCc1ccccc1)-c1nn([C@H]2CC[C@@H](CC2)N2CCN(C)CC2)c2ncnc(N)c12
InChI Key InChIKey=LGMDJFPPNVPECO-RQNOJGIXSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 8798
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
Affinity DataIC50: 12.5nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
Affinity DataIC50: 3.42E+4nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2 activity with 1mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 521nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2 with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 521nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair