BDBM99527 CHEMBL2062797::US8501936, 25

SMILES COc1ccccc1Nc1nc2c(cccn2n1)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=FTQMDBNOBLWTEF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 99527   

TargetTyrosine-protein kinase JAK2(Human)
Cephalon

US Patent
LigandChemical structure of BindingDB Monomer ID 99527BDBM99527(CHEMBL2062797 | US8501936, 25)
Affinity DataIC50: 1.32E+3nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Cephalon

US Patent
LigandChemical structure of BindingDB Monomer ID 99527BDBM99527(CHEMBL2062797 | US8501936, 25)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of human JAK2 expressed in baculovirus using biotinyl-amino-hexanoyl-EQEDEPEGDYFEWLE-amide as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Cephalon

US Patent
LigandChemical structure of BindingDB Monomer ID 99527BDBM99527(CHEMBL2062797 | US8501936, 25)
Affinity DataIC50: 1.00E+4nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Cephalon

US Patent
LigandChemical structure of BindingDB Monomer ID 99527BDBM99527(CHEMBL2062797 | US8501936, 25)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human JAK3 expressed in baculovirus using biotinyl-amino-hexanoyl-EQEDEPEGDYFEWLE-amide as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed