Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E]'
LigandChemical structure of BindingDB Monomer ID 32522BDBM32522(pyridine amide, 30)
Affinity DataIC50: 0.100nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32520BDBM32520(pyridine amide, 28)
Affinity DataIC50: 1.10nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32521BDBM32521(pyridine amide, 29)
Affinity DataIC50: 1.10nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32527BDBM32527(pyridine amide, 35)
Affinity DataIC50: 1.70nMT: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32526BDBM32526(pyridine amide, 34)
Affinity DataIC50: 2nMT: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32523BDBM32523(pyridine amide, 31)
Affinity DataIC50: 2nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32508BDBM32508(pyridine amide, 23)
Affinity DataIC50: 2.5nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32519BDBM32519(pyridine amide, 27)
Affinity DataIC50: 2.90nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32524BDBM32524(pyridine amide, 32)
Affinity DataIC50: 3.60nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32529BDBM32529(pyridine amide, 37)
Affinity DataIC50: 4.60nMT: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32525BDBM32525(pyridine amide, 33)
Affinity DataIC50: 4.70nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32528BDBM32528(pyridine amide, 36)
Affinity DataIC50: 6.5nMT: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32512BDBM32512(pyridine amide, 6)
Affinity DataIC50: 7.20nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32507BDBM32507(pyridine amide, 22)
Affinity DataIC50: 11nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32518BDBM32518(pyridine amide, 9)
Affinity DataIC50: 17nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32506BDBM32506(pyridine amide, 21)
Affinity DataIC50: 21nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32500BDBM32500(pyridine amide, 15)
Affinity DataIC50: 22nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32499BDBM32499(pyridine amide, 8)
Affinity DataIC50: 35nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32513BDBM32513(pyridine amide, 7)
Affinity DataIC50: 79nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32501BDBM32501(pyridine amide, 16)
Affinity DataIC50: 106nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32514BDBM32514(pyridine amide, 11)
Affinity DataIC50: 218nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32509BDBM32509(pyridine amide, 24)
Affinity DataIC50: 220nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32515BDBM32515(pyridine amide, 12)
Affinity DataIC50: 282nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32502BDBM32502(pyridine amide, 17)
Affinity DataIC50: 319nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32516BDBM32516(pyridine amide, 13)
Affinity DataIC50: 381nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32503BDBM32503(pyridine amide, 18)
Affinity DataIC50: 2.05E+3nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32504BDBM32504(pyridine amide, 19)
Affinity DataIC50: 2.13E+3nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32505BDBM32505(pyridine amide, 20)
Affinity DataIC50: 2.14E+3nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32510BDBM32510(pyridine amide, 25)
Affinity DataIC50: 2.35E+3nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32517BDBM32517(pyridine amide, 14)
Affinity DataIC50: 4.67E+3nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32511BDBM32511(pyridine amide, 26)
Affinity DataIC50: 1.00E+4nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed