Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1 [24-292,C272S]'
LigandChemical structure of BindingDB Monomer ID 32566BDBM32566(arylsulfonylpiperazine, 38)
Affinity DataIC50: 3nM EC50:  315nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32573BDBM32573(CHEMBL427896 | arylsulfonylpiperazine, 45)
Affinity DataIC50: 3nM EC50:  57nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32538BDBM32538(arylsulfonylpiperazine, 10)
Affinity DataIC50: 4nM EC50:  201nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32550BDBM32550(arylsulfonylpiperazine, 22)
Affinity DataIC50: 7nM EC50:  241nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32567BDBM32567(arylsulfonylpiperazine, 39)
Affinity DataIC50: 9nM EC50:  632nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32572BDBM32572(arylsulfonylpiperazine, 44)
Affinity DataIC50: 9nM EC50:  569nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32561BDBM32561(arylsulfonylpiperazine, 33)
Affinity DataIC50: 10nM EC50:  247nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32571BDBM32571(arylsulfonylpiperazine, 43)
Affinity DataIC50: 11nM EC50:  762nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32546BDBM32546(arylsulfonylpiperazine, 18)
Affinity DataIC50: 13nM EC50:  547nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32547BDBM32547(arylsulfonylpiperazine, 19)
Affinity DataIC50: 13nM EC50:  329nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32540BDBM32540(arylsulfonylpiperazine, 12)
Affinity DataIC50: 14nM EC50:  518nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32541BDBM32541(arylsulfonylpiperazine, 13)
Affinity DataIC50: 14nM EC50:  727nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32537BDBM32537(arylsulfonylpiperazine, 9)
Affinity DataIC50: 15nM EC50:  556nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32556BDBM32556(arylsulfonylpiperazine, 28)
Affinity DataIC50: 15nM EC50:  971nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32575BDBM32575(arylsulfonylpiperazine, 1)
Affinity DataIC50: 16nM EC50:  461nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32536BDBM32536(arylsulfonylpiperazine, 8)
Affinity DataIC50: 16nM EC50:  613nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32568BDBM32568(arylsulfonylpiperazine, 40)
Affinity DataIC50: 17nM EC50: >1.00E+3nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32535BDBM32535(arylsulfonylpiperazine, 7)
Affinity DataIC50: 18nM EC50:  510nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32542BDBM32542(arylsulfonylpiperazine, 14)
Affinity DataIC50: 19nM EC50:  456nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32534BDBM32534(arylsulfonylpiperazine, 6)
Affinity DataIC50: 20nM EC50:  574nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32574BDBM32574(arylsulfonylpiperazine, 46)
Affinity DataIC50: 29nM EC50:  527nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32557BDBM32557(arylsulfonylpiperazine, 29)
Affinity DataIC50: 32nM EC50:  702nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32543BDBM32543(arylsulfonylpiperazine, 15)
Affinity DataIC50: 37nM EC50:  922nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32560BDBM32560(arylsulfonylpiperazine, 32)
Affinity DataIC50: 37nM EC50:  839nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32564BDBM32564(arylsulfonylpiperazine, 36)
Affinity DataIC50: 42nM EC50: >1.00E+3nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32530BDBM32530(arylsulfonylpiperazine, 2)
Affinity DataIC50: 45nM EC50:  724nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32539BDBM32539(arylsulfonylpiperazine, 11)
Affinity DataIC50: 46nM EC50:  667nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32544BDBM32544(arylsulfonylpiperazine, 16)
Affinity DataIC50: 50nM EC50:  978nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32548BDBM32548(arylsulfonylpiperazine, 20)
Affinity DataIC50: 55nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32569BDBM32569(arylsulfonylpiperazine, 41)
Affinity DataIC50: 58nM EC50: >1.00E+3nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32570BDBM32570(arylsulfonylpiperazine, 42)
Affinity DataIC50: 62nM EC50:  638nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32549BDBM32549(arylsulfonylpiperazine, 21)
Affinity DataIC50: 64nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32545BDBM32545(arylsulfonylpiperazine, 17)
Affinity DataIC50: 74nM EC50:  603nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32562BDBM32562(arylsulfonylpiperazine, 34)
Affinity DataIC50: 87nM EC50: >1.00E+3nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32558BDBM32558(arylsulfonylpiperazine, 30)
Affinity DataIC50: 95nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32559BDBM32559(arylsulfonylpiperazine, 31)
Affinity DataIC50: 106nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32553BDBM32553(arylsulfonylpiperazine, 25)
Affinity DataIC50: 117nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32552BDBM32552(arylsulfonylpiperazine, 24)
Affinity DataIC50: 152nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32565BDBM32565(arylsulfonylpiperazine, 37)
Affinity DataIC50: 234nM EC50: >1.00E+3nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32531BDBM32531(phenylcarbonyl piperazine, 3)
Affinity DataIC50: 262nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32554BDBM32554(arylsulfonylpiperazine, 26)
Affinity DataIC50: 291nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32563BDBM32563(arylsulfonylpiperazine, 35)
Affinity DataIC50: 390nM EC50: >1.00E+3nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32533BDBM32533(benzyl piperazine, 5)
Affinity DataIC50: 550nM EC50:  1.93E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32555BDBM32555(arylsulfonylpiperazine, 27)
Affinity DataIC50: 628nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32532BDBM32532(piperazine-1-carboxamide, 4)
Affinity DataIC50: 1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 32551BDBM32551(arylsulfonylpiperazine, 23)
Affinity DataIC50: 1.00E+3nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed