Compile Data Set for Download or QSAR
Report error Found 3503 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 3A'
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Human)
University of Caen Normandy

Curated by ChEMBL
LigandPNGBDBM50058283(6-(4-Benzyl-piperazin-1-yl)-pyrido[3,2-e]pyrrolo[1...)
Affinity DataIC50: 0.000813nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Human)
University of Caen Normandy

Curated by ChEMBL
LigandPNGBDBM50408165(CHEMBL299231)
Affinity DataIC50: 0.00398nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50417287(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Affinity DataKi:  0.0316nMAssay Description:Binding affinity to 5HT3A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004276(CHEMBL111448 | 1-Isopropyl-2-oxo-1,2-dihydro-quino...)
Affinity DataKi:  0.0320nMAssay Description:Ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50060242(5-[3-(3,5-Dichloro-phenyl)-2-oxo-imidazolidin-1-yl...)
Affinity DataKi:  0.0380nMAssay Description:In vitro affinity for 5-hydroxytryptamine 3 (5-HT3) receptor by displacement of [3H]BRL-43694 from rat entorhinal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50417287(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor in rat brain cortical membranes using radioligand [3H]quipazineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50459886(CHEMBL261010)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [3H]granisetron from human 5-HT3A receptor expressed in HEK293 cells by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288283(4-Amino-N-(S)-1-aza-bicyclo[2.2.2]oct-3-yl-5-chlor...)
Affinity DataKi:  0.0500nMAssay Description:Compound was tested for its binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50397290(VUF-10147 | CHEMBL475331)
Affinity DataKi:  0.0513nMAssay Description:Displacement of [3H]granisetron from 5HT3A receptor expressed in HEK293 cells after 24 hrs by scintillation counting in presence of quipazineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288283(4-Amino-N-(S)-1-aza-bicyclo[2.2.2]oct-3-yl-5-chlor...)
Affinity DataKi:  0.0520nMAssay Description:Compound was tested for its binding affinity towards 5-HT-3 receptor in whole rat brain using (S)-[125I]-zacopride as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50334454(Ramosetron | CHEMBL1643895 | US9045501, Ramosetron)
Affinity DataKi:  0.0600nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50334454(Ramosetron | CHEMBL1643895 | US9045501, Ramosetron)
Affinity DataKi:  0.0600nM ΔG°:  -58.3kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50167011(4-(4-Methyl-piperazin-1-yl)-2,3-dihydro-1H-cyclope...)
Affinity DataKi:  0.0708nMAssay Description:Rat 5-hydroxytryptamine 3 receptor (5-HT3) antagonistMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50042715(1-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-...)
Affinity DataKi:  0.0750nMAssay Description:Displacement of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288283(4-Amino-N-(S)-1-aza-bicyclo[2.2.2]oct-3-yl-5-chlor...)
Affinity DataKi:  0.0750nMAssay Description:Compound was tested for its binding affinity towards 5-hydroxytryptamine 3 receptor in whole rat brain using [125I]DAIZAC as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50166996(2-(4-Methyl-piperazin-1-yl)-3-propyl-quinoline-4-c...)
Affinity DataKi:  0.0800nMAssay Description:Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Human)
University of Caen Normandy

Curated by ChEMBL
LigandPNGBDBM50408166(CHEMBL416662)
Affinity DataIC50: 0.0813nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM85330(NSC_68647 | CAS_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataIC50: 0.0900nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in xenopus oocytes assessed as inhibition of 5HT-induced effect by electrophysiological methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50063263(6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-ph...)
Affinity DataKi:  0.0977nMAssay Description:Rat 5-hydroxytryptamine 3 receptor (5-HT3) antagonistMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50063264(6-Piperazin-1-yl-7,8,9,10-tetrahydro-phenanthridin...)
Affinity DataKi:  0.100nMAssay Description:Rat 5-hydroxytryptamine 3 receptor (5-HT3) antagonistMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50288587(2-(4-amino-5-chloro-2,3-dihydrobenzo[b]furan-7-ylc...)
Affinity DataKi:  0.100nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50056419(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50167002(3-Methyl-2-(4-methyl-piperazin-1-yl)-quinoline-4-c...)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50083190(6-Chloro-1H-benzoimidazole-4-carboxylic acid (1-az...)
Affinity DataKi:  0.130nMAssay Description:In vitro affinity at serotonergic 5-hydroxytryptamine 3 receptor by radioligand binding assay, using [3H]-LY 278584 in rat cerebral cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50214492(CHEMBL145725 | RS-16566)
Affinity DataKi:  0.145nMAssay Description:Binding affinity for 5-hydroxytryptamine 3 receptor by displacement of [3H](R)-zacopride from ondansetron-treated NG-108-15 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2018
Entry Details

Target5-hydroxytryptamine receptor 3A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288285(N-(S)-1-Aza-bicyclo[2.2.2]oct-3-yl-5-chloro-3-iodo...)
Affinity DataKd:  0.150nMAssay Description:Compound was tested for its binding affinity towards 5-hydroxytryptamine 3 receptor in whole rat brain using (S)-[125I]-zacopride as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50282053(4-Amino-2-(1-aza-bicyclo[2.2.2]oct-3-yl)-benzo[de]...)
Affinity DataKi:  0.150nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50280507(6-Amino-2-(R)-1-aza-bicyclo[2.2.2]oct-3-yl-benzo[d...)
Affinity DataKi:  0.150nMAssay Description:Binding affinity to 5-hydroxytryptamine 3 receptor in rat entorhinal cortex using [3H]-BRL 43694 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50280507(6-Amino-2-(R)-1-aza-bicyclo[2.2.2]oct-3-yl-benzo[d...)
Affinity DataKi:  0.150nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat posterior cortex by [3H]-BRL 43694 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50227348(CHEMBL41096 | SDZ-206-830)
Affinity DataKd:  0.158nMAssay Description:Potency at neuronal 5-hydroxytryptamine 3 receptor in the rabbit heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50000523(CHEMBL544784)
Affinity DataKi:  0.160nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor in rat brain cortical membranes using radioligand [3H]quipazineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2014
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM85330(NSC_68647 | CAS_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataIC50: 0.160nMAssay Description:Binding affinity to rat 5HT3A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50000453(CHEMBL540055)
Affinity DataKi:  0.160nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor in rat brain cortical membranes using radioligand [3H]quipazineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2014
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50167013(4-Methyl-2-(4-methyl-piperazin-1-yl)-quinoline-3-c...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50307815(4-Hydroxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyc...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221600(US9303045, 87 | US9695195, 87)
Affinity DataIC50: 0.180nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50400902(CHEMBL2204360 | vortioxetine hydrobromide | 1-(2-(...)
Affinity DataIC50: 0.180nMAssay Description:Binding affinity to rat 5HT3A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 3A/3B(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50417287(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Affinity DataKd:  0.180nMAssay Description:Binding affinity to human wild type 5-HT3A/5-HT3B receptor expressed in HEK293 cells after 24 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221600(US9303045, 87 | US9695195, 87)
Affinity DataIC50: 0.180nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50056419(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
Affinity DataKi:  0.182nMAssay Description:Binding affinity for 5-hydroxytryptamine 3 receptor by displacement of [3H]-BRL 43694 from NG-108-15 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2018
Entry Details

Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50000485(CHEMBL353196 | (S)-2-(5-chlorospiro[2,3-dihydroben...)
Affinity DataKi:  0.190nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50042718(1-(3,4-Dihydro-5-thia-2a-aza-acenaphthylen-1-yl)-3...)
Affinity DataKi:  0.190nMAssay Description:Displacement of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231569(Cilansetron | KC-9946)
Affinity DataKi:  0.190nMAssay Description:The binding affinity was measured on 5-hydroxytryptamine 3 receptor using [3H]GR-65630 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50014549(CHEMBL3261480 | US9045501, 4)
Affinity DataKi:  0.200nMAssay Description:Displacement of [9-methyl-3H]BRL-43694 from human 5-HT3A receptor after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50000471(CHEMBL542900)
Affinity DataKi:  0.200nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor in rat brain cortical membranes using radioligand [3H]quipazineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2014
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50056419(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 3A/3B(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50443668(CHEBI:5537 | CHEMBL1290003 | GRANISETRON)
Affinity DataKd:  0.200nMAssay Description:Binding affinity to human wild type 5-HT3A/5-HT3B receptor expressed in HEK293 cells after 24 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221544(US9303045, 30 | US9695195, 30)
Affinity DataIC50: 0.200nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50056419(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50056419(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 as radioligand in rat posterior cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

Displayed 1 to 50 (of 3503 total ) | Next | Last >>
Jump to: