Compile Data Set for Download or QSAR
Report error Found 235 Enz. Inhib. hit(s) with Target = '5-lipoxygenase'
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038646BDBM50038646(2-(6-(4-tert-butylphenyl)-2,2-dimethyl-7-phenyl-2,...)
Affinity DataIC50: 180nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038649BDBM50038649(ML-3000 | [2-(4-Chloro-phenyl)-6,6-dimethyl-1-phen...)
Affinity DataIC50: 180nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038647BDBM50038647([2-(4-Methoxy-phenyl)-6,6-dimethyl-1-phenyl-6,7-di...)
Affinity DataIC50: 240nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043362BDBM50043362(1,8-Dihydroxy-10-[2-(3,4,5-trihydroxy-phenyl)-acet...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043360BDBM50043360(1,8-Dihydroxy-10-(4-phenyl-butyryl)-10H-anthracen-...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043353BDBM50043353(1,8-Dihydroxy-10-(3,4,5-trihydroxy-benzylidene)-10...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32020BDBM32020(LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059631BDBM50059631(6-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50: 400nMAssay Description:5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004677BDBM50004677(Acetic acid 4-acetoxy-6-chloro-2,3-dimethoxy-napht...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004677BDBM50004677(Acetic acid 4-acetoxy-6-chloro-2,3-dimethoxy-napht...)
Affinity DataIC50: 500nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059608BDBM50059608(5-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50: 500nMAssay Description:5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043357BDBM50043357(1,8-Dihydroxy-10-(3-phenyl-propionyl)-10H-anthrace...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043371BDBM50043371(1,8-Dihydroxy-10-[2-(4-methoxy-phenyl)-acetyl]-10H...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043352BDBM50043352(10-(3,4-dihydroxybenzylidene)-1,8-dihydroxyanthrac...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387594BDBM50387594(CHEMBL2057741)
Affinity DataIC50: 510nMAssay Description:Inhibition of bovine 5-LOX assessed as inhibition of calcium ionophore A23187-induced leukotriene B4 formation by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043355BDBM50043355(10-[2-(4-Benzyloxy-phenyl)-acetyl]-1,8-dihydroxy-1...)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059604BDBM50059604(4-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50: 600nMAssay Description:5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041799BDBM50041799(1,8-Dihydroxy-2-[3-(3,4,5-trihydroxy-phenyl)-propy...)
Affinity DataIC50: 600nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059616BDBM50059616(3-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50: 600nMAssay Description:5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059599BDBM50059599(4-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50: 700nMAssay Description:5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038649BDBM50038649(ML-3000 | [2-(4-Chloro-phenyl)-6,6-dimethyl-1-phen...)
Affinity DataIC50: 760nMAssay Description:Inhibition of bovine 5-LOX assessed as inhibition of calcium ionophore A23187-induced leukotriene B4 formation by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041780BDBM50041780(2-(2,5-Dihydroxy-benzyl)-1,8-dihydroxy-10H-anthrac...)
Affinity DataIC50: 900nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387596BDBM50387596(CHEMBL2057740)
Affinity DataIC50: 970nMAssay Description:Inhibition of bovine 5-LOX assessed as inhibition of calcium ionophore A23187-induced leukotriene B4 formation by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043373BDBM50043373(10-[2-(3,4-Dihydroxy-phenyl)-acetyl]-1,8-dihydroxy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043368BDBM50043368(1,8-Dihydroxy-10-[3-(4-methoxy-phenyl)-propionyl]-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059634BDBM50059634(2-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50: 1.00E+3nMAssay Description:5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059627BDBM50059627(2-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50: 1.00E+3nMAssay Description:5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043363BDBM50043363(1,8-Dihydroxy-10-[3-(4-hydroxy-phenyl)-propionyl]-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041782BDBM50041782(3-(2,5-Dihydroxy-benzyl)-1,8-dihydroxy-10H-anthrac...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32020BDBM32020(LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...)
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038653BDBM50038653([6,6-Dimethyl-2-(4-nitro-phenyl)-1-phenyl-6,7-dihy...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038645BDBM50038645([6,6-Dimethyl-2-(4-phenoxy-phenyl)-1-phenyl-6,7-di...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038654BDBM50038654(2-(6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrr...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038657BDBM50038657([2-(3-Chloro-phenyl)-6,6-dimethyl-1-phenyl-6,7-dih...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038655BDBM50038655([2-(3,4-Dichloro-phenyl)-6,6-dimethyl-1-phenyl-6,7...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038656BDBM50038656([6,6-Dimethyl-1-phenyl-2-(2,3,4-trichloro-phenyl)-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052462BDBM50052462(10-(2-Amino-phenylsulfanyl)-1,8-dihydroxy-10H-anth...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50060860BDBM50060860(anthracen-9(10H)-one | anthrone | 9(10H)-anthracen...)
Affinity DataIC50: 2.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052466BDBM50052466(3-(4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-y...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052457BDBM50052457(1,8-Dihydroxy-10-(2-hydroxy-ethylsulfanyl)-10H-ant...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043347BDBM50043347(1,8-Dihydroxy-10-(3-phenyl-propylidene)-10H-anthra...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043354BDBM50043354(1,8-Dihydroxy-10-phenylacetyl-10H-anthracen-9-one ...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043362BDBM50043362(1,8-Dihydroxy-10-[2-(3,4,5-trihydroxy-phenyl)-acet...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043367BDBM50043367(10-[2-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-acetyl]...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059623BDBM50059623(4-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracene-2-c...)
Affinity DataIC50: 2.00E+3nMAssay Description:5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041803BDBM50041803(4-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041803BDBM50041803(4-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50: 2.00E+3nMAssay Description:5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059621BDBM50059621(5-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50: 2.00E+3nMAssay Description:5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043348BDBM50043348(1,8-dihydroxy-10-(4-nitrobenzylidene)anthracen-9(1...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043352BDBM50043352(10-(3,4-dihydroxybenzylidene)-1,8-dihydroxyanthrac...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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