Compile Data Set for Download or QSAR
Report error Found 225 Enz. Inhib. hit(s) with Target = 'ATP-binding cassette sub-family C member 9/ATP-sensitive inward rectifier potassium channel 11'
LigandChemical structure of BindingDB Monomer ID 50476002BDBM50476002(CHEMBL217511)
Affinity DataEC50:  0.676nMAssay Description:Activity against pig bladder KATP channel opening assessed as ability to relax spontaneous bladder contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475970BDBM50475970(CHEMBL426334)
Affinity DataEC50:  0.912nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475995BDBM50475995(CHEMBL218564)
Affinity DataEC50:  1nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475999BDBM50475999(CHEMBL214561)
Affinity DataEC50:  1.20nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475981BDBM50475981(CHEMBL413532)
Affinity DataEC50:  1.80nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475993BDBM50475993(CHEMBL217810)
Affinity DataEC50:  2.80nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475995BDBM50475995(CHEMBL218564)
Affinity DataEC50:  3.70nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475995BDBM50475995(CHEMBL218564)
Affinity DataEC50:  3.72nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475953BDBM50475953(CHEMBL384564)
Affinity DataEC50:  3.89nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50476020BDBM50476020(CHEMBL217847)
Affinity DataEC50:  6nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475971BDBM50475971(CHEMBL386363)
Affinity DataEC50:  9.80nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475973BDBM50475973(CHEMBL265269)
Affinity DataEC50:  14nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475983BDBM50475983(CHEMBL216766)
Affinity DataEC50:  17nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50476011BDBM50476011(CHEMBL216284)
Affinity DataEC50:  18nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475982BDBM50475982(CHEMBL215375)
Affinity DataEC50:  19nMAssay Description:Activity against pig bladder KATP channel opening assessed as ability to relax spontaneous bladder contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475997BDBM50475997(CHEMBL386119)
Affinity DataEC50:  20nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475997BDBM50475997(CHEMBL386119)
Affinity DataEC50:  20nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50062397BDBM50062397(N''-cyano-N-(1,1-dimethylpropyl)-N'-pyridin-3-ylgu...)
Affinity DataEC50:  22nMAssay Description:Activity against pig bladder KATP channel opening assessed as ability to relax spontaneous bladder contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475972BDBM50475972(CHEMBL216546)
Affinity DataEC50:  22.9nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475972BDBM50475972(CHEMBL216546)
Affinity DataEC50:  23nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475972BDBM50475972(CHEMBL216546)
Affinity DataEC50:  23nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50476003BDBM50476003(CHEMBL426160)
Affinity DataEC50:  26.9nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475977BDBM50475977(CHEMBL386582)
Affinity DataEC50:  26.9nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50062397BDBM50062397(N''-cyano-N-(1,1-dimethylpropyl)-N'-pyridin-3-ylgu...)
Affinity DataKi:  27nMAssay Description:Binding affinity was determined by displacement of [3H]P1075 from its binding sites in canine cardiac membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50476003BDBM50476003(CHEMBL426160)
Affinity DataEC50:  27nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50476013BDBM50476013(CHEMBL261996)
Affinity DataEC50:  27nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475961BDBM50475961(CHEMBL214841)
Affinity DataEC50:  27.5nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475991BDBM50475991(CHEMBL320983)
Affinity DataEC50:  28nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475961BDBM50475961(CHEMBL214841)
Affinity DataEC50:  28nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475966BDBM50475966(CHEMBL384576)
Affinity DataEC50:  28nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475961BDBM50475961(CHEMBL214841)
Affinity DataEC50:  29nMAssay Description:Activity against pig bladder KATP channel opening assessed as ability to relax spontaneous bladder contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50476004BDBM50476004(CHEMBL386323)
Affinity DataEC50:  30nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50044253BDBM50044253(CHEMBL11684 | (3S,4R)-3-hydroxy-2,2-dimethyl-4-(2-...)
Affinity DataEC50:  35nMAssay Description:Activity against pig bladder KATP channel opening assessed as ability to relax spontaneous bladder contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475970BDBM50475970(CHEMBL426334)
Affinity DataEC50:  35nMAssay Description:Activity against pig bladder KATP channel opening assessed as ability to relax field-stimulated pig detrusorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50476002BDBM50476002(CHEMBL217511)
Affinity DataEC50:  45.7nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50476002BDBM50476002(CHEMBL217511)
Affinity DataEC50:  46nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475970BDBM50475970(CHEMBL426334)
Affinity DataEC50:  51nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475970BDBM50475970(CHEMBL426334)
Affinity DataEC50:  51.3nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50062397BDBM50062397(N''-cyano-N-(1,1-dimethylpropyl)-N'-pyridin-3-ylgu...)
Affinity DataEC50:  52nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475954BDBM50475954(CHEMBL216256)
Affinity DataEC50:  55nMAssay Description:Activity against pig bladder KATP channel opening assessed as ability to relax spontaneous bladder contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50476010BDBM50476010(CHEMBL412838)
Affinity DataEC50:  56nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50476014BDBM50476014(CHEMBL3138600)
Affinity DataEC50:  56nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50062402BDBM50062402(1N-cyanoimino(tert-pentylamino)methyl-3-azido-4-io...)
Affinity DataKi:  57nMAssay Description:Binding affinity was determined by displacement of [3H]P1075 from its binding sites in canine cardiac membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475992BDBM50475992(CHEMBL2112487)
Affinity DataEC50:  63nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50476000BDBM50476000(CHEMBL215996)
Affinity DataEC50:  64.6nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475958BDBM50475958(CHEMBL424726)
Affinity DataEC50:  72nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475987BDBM50475987(CHEMBL386126)
Affinity DataEC50:  72.4nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50062394BDBM50062394(1N-cyanoimino(tert-pentylamino)methyl-4-iodoanilin...)
Affinity DataKi:  74nMAssay Description:Binding affinity was determined by displacement of [3H]P1075 from its binding sites in canine cardiac membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50062397BDBM50062397(N''-cyano-N-(1,1-dimethylpropyl)-N'-pyridin-3-ylgu...)
Affinity DataEC50:  85nMAssay Description:Activity against pig bladder KATP channel opening assessed as ability to relax field-stimulated pig detrusorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50475959BDBM50475959(CHEMBL214566)
Affinity DataEC50:  91nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
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