Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with Target = 'Actin, cytoplasmic 1'
TargetActin, cytoplasmic 1(African clawed frog)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50175057(3-[(3S,6R,9R,15R,18S,21R,24R,30S,33R,36R,42R,45S,4...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against actin assembly in xenopus by polymerisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetActin, cytoplasmic 1(African clawed frog)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50175056(3-[(3S,6R,9R,15R,18S,21R,24R,30S,33R,36R,42R,45S,4...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against actin assembly in xenopus by polymerisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetActin, cytoplasmic 1(African clawed frog)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50175059(3-[(3S,6R,9R,15R,18S,21R,24R,30S,33R,36R,42R,45S,4...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against actin assembly in xenopus by polymerisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetActin, cytoplasmic 1(African clawed frog)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50175058(cyclo[L-Lys-D-Phe-D-Pro-D-Phe-L-Phe-D-Pro-L-Gln]2 ...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against actin assembly in xenopus by polymerisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetActin, cytoplasmic 1(Homo sapiens)TBA
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataKd:  4.70E+3nMAssay Description:Binding affinity against ACTB (unknown origin) assessed as apparent dissociation constant incubated for 1 hr by colloidal coomassie staining based LC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
TargetActin, cytoplasmic 1(Homo sapiens)TBA
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataIC50: 8.84E+3nMAssay Description:Inhibition of ACTB (unknown origin) incubated for 1 hr by colloidal coomassie staining based LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details