Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with Target = 'Adenylate cyclase type 1/2/3/4/5/6/7/8/9'
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144001BDBM50144001(3-{4-[1-(2',4'-Dichloro-biphenyl-4-ylcarbamoyl)-he...)
Affinity DataKi:  14nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144020BDBM50144020(3-{4-[1-(4-Benzofuran-2-yl-phenylcarbamoyl)-heptyl...)
Affinity DataKi:  17nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144015BDBM50144015(3-{4-[2-(4-Benzofuran-2-yl-phenylcarbamoyl)-octyl]...)
Affinity DataKi:  20nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144008BDBM50144008(3-{4-[2-(4-Benzofuran-2-yl-phenylcarbamoyl)-2-(4-t...)
Affinity DataKi:  29nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144002BDBM50144002(3-{4-[2-(4-tert-Butyl-phenyl)-2-(2',4'-dichloro-bi...)
Affinity DataKi:  33nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144008BDBM50144008(3-{4-[2-(4-Benzofuran-2-yl-phenylcarbamoyl)-2-(4-t...)
Affinity DataKi:  69nMAssay Description:In vitro inhibitory activity against glucagon induced monkey adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004822BDBM50004822(CHEMBL24077 | SKF 38393 (+) | SK-383933 | R(+)SKF ...)
Affinity DataEC50:  71nMAssay Description:Compound was tested for the adenylate cyclase stimulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144003BDBM50144003(3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-trifluoromethox...)
Affinity DataKi:  110nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144016BDBM50144016(3-{4-[(Biphenyl-4-ylcarbamoyl)-(4-tert-butyl-pheny...)
Affinity DataKi:  144nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144009BDBM50144009(3-{4-[1-(4-tert-Butyl-cyclohexyl)-3-(4-trifluorome...)
Affinity DataKi:  254nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144004BDBM50144004(3-{4-[2-(Biphenyl-4-ylcarbamoyl)-2-(4-tert-butyl-p...)
Affinity DataKi:  300nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144012BDBM50144012(4-[(Biphenyl-4-ylcarbamoyl)-(4-tert-butyl-phenyl)-...)
Affinity DataKi:  317nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144006BDBM50144006(3-{4-[2-(4-tert-Butyl-phenyl)-2-(quinolin-3-ylcarb...)
Affinity DataKi:  610nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144005BDBM50144005(3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-hydroxymethyl-p...)
Affinity DataKi:  1.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144014BDBM50144014(3-{4-[2-(4-tert-Butyl-phenyl)-3-(4-ethyl-piperazin...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144010BDBM50144010(3-{4-[(Biphenyl-4-ylcarbamoyl)-(4-tert-butyl-pheny...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144013BDBM50144013(3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-trifluoromethox...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144011BDBM50144011(3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-ethyl-phenylcar...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144018BDBM50144018(3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-pyrazol-1-yl-ph...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144007BDBM50144007(3-{4-[2-(4-tert-Butyl-phenyl)-2-(3-ethyl-phenylcar...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144000BDBM50144000(3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-piperidin-1-yl-...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144019BDBM50144019(3-{4-[(Biphenyl-4-ylcarbamoyl)-(4-tert-butyl-pheny...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144017BDBM50144017(3-{4-[2-(4-tert-Butyl-phenyl)-3-oxo-3-(4-p-tolyl-p...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004821BDBM50004821(SK-39315A | 2,3,4,5-Tetrahydro-1H-benzo[d]azepine-...)
Affinity DataEC50:  5.20E+3nMAssay Description:Compound was tested for the adenylate cyclase stimulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230364BDBM50230364(CHEMBL146629)
Affinity DataEC50: >1.00E+4nMAssay Description:Compound was tested for the adenylate cyclase stimulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50227472BDBM50227472(CHEMBL2372272)
Affinity DataKi:  4.40E+6nMAssay Description:In vitro antagonist activity was measured by inhibition of vasopressin-stimulated adenylate cyclase in renal medullary preparation in pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed