Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with Target = 'Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase'
LigandChemical structure of BindingDB Monomer ID 50117663BDBM50117663(CHEMBL3613707)
Affinity DataIC50: 6nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117662BDBM50117662(CHEMBL3613706)
Affinity DataIC50: 6nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117662BDBM50117662(CHEMBL3613706)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117663BDBM50117663(CHEMBL3613707)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50433269BDBM50433269(CHEMBL2376303)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant MGAT3 expressed in insect cell membrane using 2-oleyl-sn-glycerol and [14C]-oleyl-coenzyme A as substrate after 10 to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117668BDBM50117668(CHEMBL3613712)
Affinity DataIC50: 63nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117668BDBM50117668(CHEMBL3613712)
Affinity DataIC50: 63nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117667BDBM50117667(CHEMBL3613711)
Affinity DataIC50: 72nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117667BDBM50117667(CHEMBL3613711)
Affinity DataIC50: 79nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117665BDBM50117665(CHEMBL3613709)
Affinity DataIC50: 92nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117665BDBM50117665(CHEMBL3613709)
Affinity DataIC50: 100nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50433274BDBM50433274(CHEMBL2376321)
Affinity DataIC50: 126nMAssay Description:Inhibition of human recombinant MGAT3 expressed in insect cell membrane using 2-oleyl-sn-glycerol and [14C]-oleyl-coenzyme A as substrate after 10 to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117665BDBM50117665(CHEMBL3613709)
Affinity DataIC50: 204nMAssay Description:Inhibition of human MGAT3 expressed in HEK293 cells assessed as effect on incorporation of [1,3-14C] glycerol into TAG by TLC method in presence of D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117665BDBM50117665(CHEMBL3613709)
Affinity DataIC50: 205nMAssay Description:Inhibition of human MGAT3 expressed in HEK293 cells assessed as effect on incorporation of [1,3-14C] glycerol into TAG by TLC method in presence of D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117666BDBM50117666(CHEMBL3613710)
Affinity DataIC50: 365nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117668BDBM50117668(CHEMBL3613712)
Affinity DataIC50: 389nMAssay Description:Inhibition of human MGAT3 expressed in HEK293 cells assessed as effect on incorporation of [1,3-14C] glycerol into TAG by TLC method in presence of D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117668BDBM50117668(CHEMBL3613712)
Affinity DataIC50: 394nMAssay Description:Inhibition of human MGAT3 expressed in HEK293 cells assessed as effect on incorporation of [1,3-14C] glycerol into TAG by TLC method in presence of D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117666BDBM50117666(CHEMBL3613710)
Affinity DataIC50: 398nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50433272BDBM50433272(CHEMBL2376325)
Affinity DataIC50: 398nMAssay Description:Inhibition of human recombinant MGAT3 expressed in insect cell membrane using 2-oleyl-sn-glycerol and [14C]-oleyl-coenzyme A as substrate after 10 to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117664BDBM50117664(CHEMBL3613708)
Affinity DataIC50: 597nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117664BDBM50117664(CHEMBL3613708)
Affinity DataIC50: 631nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117659BDBM50117659(CHEMBL3613703)
Affinity DataIC50: 631nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117659BDBM50117659(CHEMBL3613703)
Affinity DataIC50: 682nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117667BDBM50117667(CHEMBL3613711)
Affinity DataIC50: 760nMAssay Description:Inhibition of human MGAT3 expressed in HEK293 cells assessed as effect on incorporation of [1,3-14C] glycerol into TAG by TLC method in presence of D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117667BDBM50117667(CHEMBL3613711)
Affinity DataIC50: 794nMAssay Description:Inhibition of human MGAT3 expressed in HEK293 cells assessed as effect on incorporation of [1,3-14C] glycerol into TAG by TLC method in presence of D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 201239BDBM201239(US9187424, 6-2)
Affinity DataIC50: 820nMAssay Description:Inhibition of human MGAT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50579519BDBM50579519(CHEMBL3912712)
Affinity DataIC50: 820nMAssay Description:Inhibition of human MGAT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50579526BDBM50579526(CHEMBL4878564)
Affinity DataIC50: 820nMAssay Description:Inhibition of human MGAT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50433273BDBM50433273(CHEMBL2376322)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human recombinant MGAT3 expressed in insect cell membrane using 2-oleyl-sn-glycerol and [14C]-oleyl-coenzyme A as substrate after 10 to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117660BDBM50117660(CHEMBL3613704)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117660BDBM50117660(CHEMBL3613704)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117661BDBM50117661(CHEMBL3613705)
Affinity DataIC50: 3.84E+3nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117661BDBM50117661(CHEMBL3613705)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 289003BDBM289003(US10093650, Example 16 | US10093650, Example 14 | ...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of recombinant human MGAT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50090510BDBM50090510(CHEMBL3581716)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro inhibition of full length human MGAT3 transfected in Sf-21 cells using [1-14C]oleoyl-CoA assessed as incorporation of radioactivity into lip...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 276750BDBM276750(US10071992, Example 3.4 | (S)-2-(5-((3-ethoxypyrid...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human MGAT3 using [1-14C]decanoyl-CoA and 1,2-didecanoyl-sn-glycerol as substrates assessed as incorporation of [1-14C]decanoyl into di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 276748BDBM276748(US10071992, Example 3.5 | US10071992, Example 5 | ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human MGAT3 using [1-14C]decanoyl-CoA and 1,2-didecanoyl-sn-glycerol as substrates assessed as incorporation of [1-14C]decanoyl into di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 504484BDBM504484(2-{5-[(3-Ethoxypyridin-2-yl)oxy]pyridin-3-yl}-N-[(...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MGAT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed