TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Binding affinity to human recombinant BHMT expressed in Escherichia coli using variable levels of betaine substrate by Dixon plotMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibition of human BHMTMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of human recombinant BHMT using N-methyl-[14C]-betaine/D,L-homocysteine as substrate after 30 mins by scintiillation counting analysisMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 96nMAssay Description:Inhibition of human BHMTMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 138nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 139nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human BHMTMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 649nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 701nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant BHMT using N-methyl-[14C]-betaine/D,L-homocysteine as substrate after 30 mins by scintiillation counting analysisMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human BHMTMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant BHMT using N-methyl-[14C]-betaine/D,L-homocysteine as substrate after 30 mins by scintiillation counting analysisMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human BHMTMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human BHMTMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 7.66E+4nMAssay Description:Inhibition of recombinant human BHMT expressed in Escherichia coli BL31(DE3)More data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 2.19E+5nMAssay Description:Inhibition of human recombinant BHMT using N-methyl-[14C]-betaine/D,L-homocysteine as substrate after 30 mins by scintiillation counting analysisMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKd: 280nMAssay Description:Binding affinity to human recombinant BHMT expressed in Escherichia coli by intrinsic tryptophan fluorescence studiesMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKd: 83nMAssay Description:Binding affinity to human recombinant BHMT expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair