Compile Data Set for Download or QSAR
Report error Found 758 Enz. Inhib. hit(s) with Target = 'Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN'
LigandPNGBDBM734818(US20250129069, Compound I-55)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM717001(N-(2-chloro-4-(trifluoromethyl)phenyl)-2-(6-ethyl-...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM716868(N-(2-chloro-4-(trifluoromethyl)phenyl)-2-(6-ethyl-...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM716869(N-(2-chloro-4-(trifluoromethyl)phenyl)-2-(2-(cyclo...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM734940(US20250129069, Compound I-177)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM717011(N-[2-chloro-4-(trifluoromethyl)phenyl]-2-{6-ethyl-...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM734825(US20250129069, Compound I-62)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM734952(US20250129069, Compound I-189)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM734822(US20250129069, Compound I-59)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM734820(US20250129069, Compound I-57)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM717110(N-[2-chloro-4-(trifluoromethyl)phenyl]-2-{6-ethyl-...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM716995(N-[2-chloro-4-(trifluoromethyl)phenyl]-2-[2-(cyclo...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM734934(US20250129069, Compound I-171)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM734979(US20250129069, Compound I-216)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM734978(US20250129069, Compound I-215)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM734848(US20250129069, Compound I-85)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM734846(US20250129069, Compound I-83)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM717031(N-[2-chloro-4-(trifluoromethyl)phenyl]-2-{2- [cycl...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM734974(US20250129069, Compound I-211)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM734845(US20250129069, Compound I-82)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM734859(US20250129069, Compound I-96)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM734858(US20250129069, Compound I-95)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM734854(US20250129069, Compound I-91)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM734958(US20250129069, Compound I-195)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM717022(2-(2-(2-azabicyclo[3.1.0]hexan-2-yl)-6-ethyl-7-((S...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM717023(N-[2-chloro-4-(trifluoromethyl)phenyl]-2-{2- [cycl...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM734836(US20250129069, Compound I-73)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM717021(2-(2-(2-azabicyclo[3.1.0]hexan-2-yl)-6-ethyl-7-((S...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM716936(N-(2-chloro-4-(trifluoromethyl)phenyl)-2-(2-(dimet...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM734890(US20250129069, Compound I-127)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM734889(US20250129069, Compound I-126)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM716942(N-(2-chloro-4-(trifluoromethyl)phenyl)-2-(6-ethyl-...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM716940(N-(2-chloro-4-(trifluoromethyl)phenyl)-2-(7-ethyl-...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM717068(N-[2-chloro-4-(trifluoromethyl)phenyl]-2-{6-ethyl-...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM734865(US20250129069, Compound I-102)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM717048(2-(2-(2-azabicyclo[3.1.0]hexan-2-yl)-6-ethyl-7-((1...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM717046(2-{7-[4-(4-chloro-3-hydroxypyridine-2-carbonyl)pip...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM717047(2-(2-(2-azabicyclo[3.1.0]hexan-2-yl)-6-ethyl-7-((1...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM716931(N-(2-chloro-4-(trifluoromethyl)phenyl)-2-(2-cyclop...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM716929(N-(2-chloro-4-(trifluoromethyl)phenyl)-2-(2-cyclop...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM734872(US20250129069, Compound I-109)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM717054(N-[2-chloro-4-(trifluoromethyl)phenyl]-2-{6-ethyl-...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM717055(N-[2-chloro-4-(trifluoromethyl)phenyl]-2-{6-ethyl-...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM734915(US20250129069, Compound I-152)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM734786(US20250129069, Compound I-23)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM716971(N-[2-chloro-4-(trifluoromethyl)phenyl]-2-{6-ethyl-...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

LigandPNGBDBM734912(US20250129069, Compound I-149)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM734783(US20250129069, Compound I-20)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM734910(US20250129069, Compound I-147)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details

LigandPNGBDBM717095(N-[2-chloro-4-(trifluoromethyl)phenyl]-2-{6-ethyl-...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

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