Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with Target = 'Biotinidase'
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 480933BDBM480933(US10906888, Example 147)
Affinity DataIC50: 40nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 480971BDBM480971(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[1-(pyrimidin-5-y...)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 480917BDBM480917(7-oxa-2-azaspiro[3.5]non-2-yl(2-{[2-(pyrazin-2-yl)...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 480919BDBM480919(US10906888, Example 133)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 480929BDBM480929(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[2-(pyrimidin-5-y...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 480931BDBM480931(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[(1S)-1-(pyrazin-...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 480965BDBM480965(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[2-(pyrazin-2-yl)...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 480921BDBM480921(US10906888, Example 135)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50585537BDBM50585537(CHEMBL5084938)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 480968BDBM480968(US10906888, Example 185)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 480783BDBM480783(US10906888, Example 1)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50585533BDBM50585533(CHEMBL5094835)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 480981BDBM480981(US10906888, Example 200 | US10906888, Example 199 ...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 480973BDBM480973(US10906888, Example 190)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 394644BDBM394644(US10308615, Example 1 | 3-[(2-{[1-(pyrimidin-5-yl)...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 480990BDBM480990(US10906888, Example 150)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 480932BDBM480932(US10906888, Example 146)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 480928BDBM480928(8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 480978BDBM480978(US10906888, Example 196 | US10906888, Example 197 ...)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50585535BDBM50585535(CHEMBL5086259)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed