Compile Data Set for Download or QSAR
Report error Found 107 Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 3 [51-123]'
TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179480BDBM179480(US9675697, Cpd. No. 68)
Affinity DataKi:  5.10nM ΔG°:  -47.3kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179485BDBM179485(US9675697, Cpd. No. 183)
Affinity DataKi:  6.10nM ΔG°:  -46.9kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179638BDBM179638(US9675697, Cpd. No. 319)
Affinity DataKi:  6.30nM ΔG°:  -46.8kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 50092310BDBM50092310(US9675697, Cpd. No. 23 | CHEMBL3581661)
Affinity DataKi:  7.30nM ΔG°:  -46.4kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179633BDBM179633(US9675697, Cpd. No. 316)
Affinity DataKi:  7.5nM ΔG°:  -46.4kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179639BDBM179639(US9675697, Cpd. No. 322)
Affinity DataKi:  7.70nM ΔG°:  -46.3kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179490BDBM179490(US9675697, Cpd. No. 196)
Affinity DataKi:  9.70nM ΔG°:  -45.7kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179474BDBM179474(US9675697, Cpd. No. 25)
Affinity DataKi:  10nM ΔG°:  -45.7kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179492BDBM179492(US9675697, Cpd. No. 207)
Affinity DataKi:  10nM ΔG°:  -45.7kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179574BDBM179574(US9675697, Cpd. No. 212)
Affinity DataKi:  10nM ΔG°:  -45.7kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKi:  10nM ΔG°:  -45.7kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179491BDBM179491(US9675697, Cpd. No. 197)
Affinity DataKi:  11nM ΔG°:  -45.4kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179493BDBM179493(US9675697, Cpd. No. 211)
Affinity DataKi:  11nM ΔG°:  -45.4kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 50092341BDBM50092341(US9675697, Cpd. No. 22 | CHEMBL3581660)
Affinity DataKi:  13nM ΔG°:  -45.0kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179627BDBM179627(US9675697, Cpd. No. 213)
Affinity DataKi:  14nM ΔG°:  -44.8kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 50092324BDBM50092324(US9675697, Cpd. No. 1 | CHEMBL3581655)
Affinity DataKi:  15nM ΔG°:  -44.7kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179477BDBM179477(US9675697, Cpd. No. 44)
Affinity DataKd:  17nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 50092310BDBM50092310(US9675697, Cpd. No. 23 | CHEMBL3581661)
Affinity DataKd:  18nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 50092341BDBM50092341(US9675697, Cpd. No. 22 | CHEMBL3581660)
Affinity DataKd:  18nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179474BDBM179474(US9675697, Cpd. No. 25)
Affinity DataKd:  21nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179637BDBM179637(US9675697, Cpd. No. 317)
Affinity DataKi:  23nM ΔG°:  -43.6kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179640BDBM179640(US9675697, Cpd. No. 352)
Affinity DataKi:  32nM ΔG°:  -42.8kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 50092323BDBM50092323(US9675697, Cpd. No. 21 | CHEMBL3581656)
Affinity DataKi:  32nM ΔG°:  -42.8kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 50092316BDBM50092316(US9675697, Cpd. No. 24 | CHEMBL3581658)
Affinity DataKi:  38nM ΔG°:  -42.4kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 543479BDBM543479(US11279703, Table 1.2 | US11279703, TABLE 6.320 | ...)
Affinity DataIC50: 49nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 543481BDBM543481(US11279703, Table 1.4 | US11279703, TABLE 6.353 | ...)
Affinity DataIC50: 59nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 543677BDBM543677(US11279703, TABLE 6.266)
Affinity DataIC50: 78nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 50365262BDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 80nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 205429BDBM205429( (R)-JQ1 (3) | US9320741, (R)-JQ1 | US10407441, Co...)
Affinity DataIC50: 81nMAssay Description:Determine the binding ability of BRD4 compounds to bromodomains of BRD2 and BRD4. 96 well plate based commercial TR-FRET Assay kits (Cayman Chemical,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2022
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 543776BDBM543776(US11279703, TABLE 6.388 | US11279703, TABLE 6.366)
Affinity DataIC50: 81nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 543776BDBM543776(US11279703, TABLE 6.388 | US11279703, TABLE 6.366)
Affinity DataIC50: 83nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 543638BDBM543638(US11279703, TABLE 6.227)
Affinity DataIC50: 89nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 543570BDBM543570(US11279703, TABLE 6.159 | US11643396, Example SG4-...)
Affinity DataIC50: 92nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 543789BDBM543789(US11279703, TABLE 6.379 | US11279703, TABLE 6.380)
Affinity DataIC50: 97nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 313778BDBM313778(US10167292, Example 13)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 313791BDBM313791(US10167292, Example 35)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 313779BDBM313779(US10167292, Example 16)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 313792BDBM313792(US10167292, Example 36)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 313773BDBM313773(US10167292, Example 7)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 313783BDBM313783(US10167292, Example 23)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 313796BDBM313796(US10167292, Example 40)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 313777BDBM313777(US10167292, Example 12)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 313790BDBM313790(US10167292, Example 34)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 313784BDBM313784(US10167292, Example 24)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 313771BDBM313771(US10167292, Example 5)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 313788BDBM313788(US10167292, Example 32)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 313775BDBM313775(US10167292, Example 10)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 313782BDBM313782(US10167292, Example 22)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 313795BDBM313795(US10167292, Example 39)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 543797BDBM543797(US11279703, TABLE 6.387)
Affinity DataIC50: 100nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

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