Compile Data Set for Download or QSAR
Report error Found 357 Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [353-454]'
TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528638BDBM528638(US11192900, Compound 584 | US11192900, Example S-6...)
Affinity DataIC50: 1nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528643BDBM528643(US11192900, Compound 611 | US11192900, Example S-6...)
Affinity DataIC50: 2nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528646BDBM528646(US11192900, Compound 406 | US11192900, Example S-7...)
Affinity DataIC50: 3nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528648BDBM528648(US11192900, Compound 616 | US11192900, Compound 70...)
Affinity DataIC50: 4nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528627BDBM528627(US11192900, Compound 412 | US11192900, Example S-5...)
Affinity DataIC50: 4nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528647BDBM528647(US11192900, Compound 661 | US11192900, Example S-7...)
Affinity DataIC50: 5nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528641BDBM528641(US11192900, Compound 588 | US11192900, Example S-6...)
Affinity DataIC50: 6nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528629BDBM528629(US11192900, Compound 411 | US11192900, Example S-5...)
Affinity DataIC50: 10nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528602BDBM528602(US11192900, Compound 21 | US11192900, Example S-28)
Affinity DataIC50: 11nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528640BDBM528640(US11192900, Compound 587 | US11192900, Example S-6...)
Affinity DataIC50: 11nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528651BDBM528651(US11192900, Compound 570 | US11192900, Example S-7...)
Affinity DataIC50: 11nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528624BDBM528624(US11192900, Compound 407 | US11192900, Example S-4...)
Affinity DataIC50: 11nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528642BDBM528642(US11192900, Compound 589 | US11192900, Example S-6...)
Affinity DataIC50: 12nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528632BDBM528632(US11192900, Compound 381 | US11192900, Example S-5...)
Affinity DataIC50: 13nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528590BDBM528590(US11192900, Compound 11 | US11192900, Example S-18)
Affinity DataIC50: 14nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528612BDBM528612(US11192900, Compound 29 | US11192900, Example S-36)
Affinity DataIC50: 15nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528587BDBM528587(US11192900, Compound 8 | US11192900, Example S-15)
Affinity DataIC50: 17nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528636BDBM528636(US11192900, Compound 167 | US11192900, Example S-6...)
Affinity DataIC50: 17nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528580BDBM528580(US11192900, Compound 3 | US11192900, Example S-10)
Affinity DataIC50: 21nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528580BDBM528580(US11192900, Compound 3 | US11192900, Example S-10)
Affinity DataIC50: 21nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528583BDBM528583(US11192900, Compound 4 | US11192900, Example S-11)
Affinity DataIC50: 22nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528586BDBM528586(US11192900, Compound 7 | US11192900, Example S-14)
Affinity DataIC50: 24nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528592BDBM528592(US11192900, Compound 13 | US11192900, Example S-20)
Affinity DataIC50: 24nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528596BDBM528596(US11192900, Compound 16 | US11192900, Example S-23)
Affinity DataIC50: 26nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528645BDBM528645(US11192900, Compound 613 | US11192900, Example S-6...)
Affinity DataIC50: 27nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528595BDBM528595(US11192900, Compound 15 | US11192900, Example S-22)
Affinity DataIC50: 34nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528591BDBM528591(US11192900, Compound 12 | US11192900, Example S-19)
Affinity DataIC50: 37nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528639BDBM528639(US11192900, Compound 585 | US11192900, Example S-6...)
Affinity DataIC50: 43nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528589BDBM528589(US11192900, Compound 10 | US11192900, Example S-17)
Affinity DataIC50: 56nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528613BDBM528613(US11192900, Compound 30 | US11192900, Example S-37)
Affinity DataIC50: 57nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528581BDBM528581(US11192900, Compound 1 | US11192900, Example S-8)
Affinity DataIC50: 64nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528617BDBM528617(US11192900, Compound 409 | US11192900, Example S-4...)
Affinity DataIC50: 75nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528637BDBM528637(US11192900, Compound 583 | US11192900, Example S-6...)
Affinity DataIC50: 78nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528631BDBM528631(US11192900, Compound 86 | US11192900, Example S-55)
Affinity DataIC50: 80nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 528648BDBM528648(US11192900, Compound 616 | US11192900, Compound 70...)
Affinity DataIC50: 93nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 318725BDBM318725(US9624241, Example 257 | 7-(3,5-dimethylisoxazol-4...)
Affinity DataIC50: 100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 318468BDBM318468(7-(3,5-Dimethylisoxazol-4-yl)-4-pyridin-2-yl-4,5-d...)
Affinity DataIC50: 100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 318724BDBM318724(US9624241, Example 256 | 7-(3,5-dimethylisoxazol-4...)
Affinity DataIC50: 100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 318471BDBM318471(4-Cyclohexyl-7-(3,5-dimethylisoxazol-4-yl)-4,5-dih...)
Affinity DataIC50: 100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 318727BDBM318727(US9624241, Example 259 | (4S)-7-(3,5-dimethylisoxa...)
Affinity DataIC50: 100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 318468BDBM318468(7-(3,5-Dimethylisoxazol-4-yl)-4-pyridin-2-yl-4,5-d...)
Affinity DataIC50: 100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 318472BDBM318472(7-(3,5-Dimethylisoxazol-4-yl)-4-(tetrahydrofuran-2...)
Affinity DataIC50: 100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 318729BDBM318729(US9624241, Example 261 | (4S)-7-(3,5-dimethylisoxa...)
Affinity DataIC50: 100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 318473BDBM318473(7-(3,5-Dimethylisoxazol-4-yl)-4-(tetrahydrofuran-2...)
Affinity DataIC50: 100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 318728BDBM318728(US9624241, Example 260 | (4S)-7-(3,5-dimethylisoxa...)
Affinity DataIC50: 100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 318475BDBM318475(2-{2-[7-(3,5-Dimethylisoxazol-4-yl)-2-oxo-1,2,4,5-...)
Affinity DataIC50: 100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 318731BDBM318731(US9624241, Example 263 | 7-(3,5-dimethylisoxazol-4...)
Affinity DataIC50: 100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 318474BDBM318474(7-(3,5-Dimethylisoxazol-4-yl)-4-(1,3-thiazol-2-yl)...)
Affinity DataIC50: 100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 318730BDBM318730(US9624241, Example 262 | 9-(anilinomethyl)-7-(3,5-...)
Affinity DataIC50: 100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 318461BDBM318461(7-(3,5-Dimethylisoxazol-4-yl)-4-(3-methoxyphenyl)-...)
Affinity DataIC50: 100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent

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