Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon'
LigandChemical structure of BindingDB Monomer ID 511627BDBM511627(US11059801, Compound dBET35)
Affinity DataIC50: 7.21nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511610BDBM511610(US11059801, Compound dBET18)
Affinity DataIC50: 11nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511629BDBM511629(US11059801, Compound dBET37)
Affinity DataIC50: 13.2nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511598BDBM511598(US11059801, Compound dBET6)
Affinity DataIC50: 14nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511601BDBM511601(US11059801, Compound dBET9)
Affinity DataIC50: 15nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50544938BDBM50544938(CHEMBL4094346 | US11059801, Compound dBET1)
Affinity DataIC50: 20nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511634BDBM511634(US11059801, Compound dBET43)
Affinity DataIC50: 24.5nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511633BDBM511633(US11059801, Compound dBET42)
Affinity DataIC50: 26.9nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511635BDBM511635(US11059801, Compound dBET44)
Affinity DataIC50: 30nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511607BDBM511607(US11059801, Compound dBET15)
Affinity DataIC50: 31nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511630BDBM511630(US11059801, Compound dBET38)
Affinity DataIC50: 31.4nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511595BDBM511595(US11059801, Compound dBET3)
Affinity DataIC50: 32nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511597BDBM511597(US11059801, Compound dBET5)
Affinity DataIC50: 33nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511609BDBM511609(US11059801, Compound dBET17)
Affinity DataIC50: 46nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511632BDBM511632(US11059801, Compound dBET41)
Affinity DataIC50: 62.8nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511628BDBM511628(US11059801, Compound dBET36)
Affinity DataIC50: 80.3nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511602BDBM511602(US11059801, Compound dBET10)
Affinity DataIC50: 83nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511631BDBM511631(US11059801, Compound dBET40)
Affinity DataIC50: 89.5nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511594BDBM511594(US11059801, Compound dBET2)
Affinity DataIC50: 134nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511599BDBM511599(US11059801, Compound dBET7)
Affinity DataIC50: 161nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511613BDBM511613(US11059801, Compound dBET21)
Affinity DataIC50: 175nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511617BDBM511617(US11059801, Compound dBET25)
Affinity DataIC50: 182nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511611BDBM511611(US11059801, Compound dBET19)
Affinity DataIC50: 212nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511600BDBM511600(US11059801, Compound dBET8)
Affinity DataIC50: 269nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511618BDBM511618(US11059801, Compound dBET26)
Affinity DataIC50: 282nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511603BDBM511603(US11059801, Compound dBET11)
Affinity DataIC50: 958nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511626BDBM511626(US11059801, Compound dBET34)
Affinity DataIC50: 1.54E+3nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511604BDBM511604(US11059801, Compound dBET12)
Affinity DataIC50: 2.08E+3nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511637BDBM511637(US11059801, Compound dBET46)
Affinity DataIC50: 2.23E+3nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511608BDBM511608(US11059801, Compound dBET16)
Affinity DataIC50: 2.28E+3nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511624BDBM511624(US11059801, Compound dBET32)
Affinity DataIC50: 3.30E+3nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511625BDBM511625(US11059801, Compound dBET33)
Affinity DataIC50: 4.99E+3nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511612BDBM511612(US11059801, Compound dBET20)
Affinity DataIC50: 5.70E+3nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511596BDBM511596(US11059801, Compound dBET4)
Affinity DataIC50: 6.87E+3nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511605BDBM511605(US11059801, Compound dBET13)
Affinity DataIC50: 6.93E+3nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511606BDBM511606(US11059801, Compound dBET14)
Affinity DataIC50: 8.83E+3nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 511636BDBM511636(US11059801, Compound dBET45)
Affinity DataIC50: 1.54E+4nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent