Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 7'
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50088301BDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of CCR7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306033BDBM50306033(Cenicriviroc | TAK-652 | TBR-652)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of CCR7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666785BDBM50666785(CHEMBL6177821)
Affinity DataKi:  6.5nMAssay Description:Displacement of Mz437 from CCR7 in live HEK293T cells expressing CCR7_GSSG_Nluc assessed as inhibition constant using furimazine as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666785BDBM50666785(CHEMBL6177821)
Affinity DataKi:  9.90nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200882BDBM50200882((R)-3-(2-(2,2-dimethyl-1-(5-methylfuran-2-yl)propy...)
Affinity DataKi:  14nMAssay Description:Displacement of Mz437 from CCR7 in live HEK293T cells expressing CCR7_GSSG_Nluc assessed as inhibition constant using furimazine as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666786BDBM50666786(CHEMBL6174303)
Affinity DataKi:  20nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666784BDBM50666784(CHEMBL5433301)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at CCR7 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200882BDBM50200882((R)-3-(2-(2,2-dimethyl-1-(5-methylfuran-2-yl)propy...)
Affinity DataKi:  36nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666783BDBM50666783(CHEMBL6177412)
Affinity DataKd:  52nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as kinetic dissociation cons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666783BDBM50666783(CHEMBL6177412)
Affinity DataKd:  70nMAssay Description:Displacement of Mz437 from CCR7 in live HEK293T cells expressing CCR7_GSSG_Nluc assessed as equilibrium dissociation constant using furimazine as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666784BDBM50666784(CHEMBL5433301)
Affinity DataKi:  77nMAssay Description:Displacement of Mz437 from CCR7 in live HEK293T cells expressing CCR7_GSSG_Nluc assessed as inhibition constant using furimazine as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666794BDBM50666794(Pf-07054894)
Affinity DataKi:  81nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666784BDBM50666784(CHEMBL5433301)
Affinity DataKi:  99nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666783BDBM50666783(CHEMBL6177412)
Affinity DataKd:  212nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as equilibrium dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666795BDBM50666795(CHEMBL6175205)
Affinity DataKi:  504nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666787BDBM50666787(CHEMBL6176121)
Affinity DataKi:  1.09E+3nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200882BDBM50200882((R)-3-(2-(2,2-dimethyl-1-(5-methylfuran-2-yl)propy...)
Affinity DataIC50: 1.28E+3nMAssay Description:Antagonist activity at human CCR7 expressed in HEK293T cells assessed as inhibition of CCL19 mediated Galpha-o activation using Nano-glo nanolucifera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200888BDBM50200888((R)-2-hydroxy-N,N-dimethyl-3-(2-(2-methyl-1-(5-met...)
Affinity DataKi:  1.52E+3nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200880BDBM50200880(2-hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5-methylfuran...)
Affinity DataKi:  1.69E+3nMAssay Description:Displacement of Mz437 from CCR7 in live HEK293T cells expressing CCR7_GSSG_Nluc assessed as inhibition constant using furimazine as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623727BDBM50623727(CHEMBL5440411)
Affinity DataIC50: 1.78E+3nMAssay Description:Competitive binding affinity to CCR7 in human U87 cells preincubated for 15 mins followed by CCL19 AF647 addition measured after 30 mins by flow cyto...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666788BDBM50666788(CHEMBL6174362)
Affinity DataKi:  2.57E+3nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200881BDBM50200881((R)-3-(2-(cyclopropyl(5-methylfuran-2-yl)methylami...)
Affinity DataKi:  2.89E+3nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246956BDBM50246956(1,3-dicyclohexyl-2-((5,6-dihydroimidazo[2,1-b]thia...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CCR7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666789BDBM50666789(CHEMBL6177696)
Affinity DataKi:  4.20E+3nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666792BDBM50666792(CHEMBL6175062)
Affinity DataKi:  5.10E+3nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666791BDBM50666791(CHEMBL6177695)
Affinity DataKi:  5.19E+3nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200880BDBM50200880(2-hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5-methylfuran...)
Affinity DataKi:  7.79E+3nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200880BDBM50200880(2-hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5-methylfuran...)
Affinity DataKi:  7.79E+3nMAssay Description:Binding affinity to CCR7 (unknown origin) assessed as inhibition constant by NanoBERT competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666793BDBM50666793(CHEMBL6176139)
Affinity DataKi:  9.10E+3nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666790BDBM50666790(CHEMBL6173855)
Affinity DataKi:  9.27E+3nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50463591BDBM50463591(CHEMBL4248604)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human CCR7 expressed in CHO cells assessed as decrease in CCL19-induced reduction of forskolin-stimulated cAMP accumulation preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50255479BDBM50255479(CHEMBL4067429)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at CCR7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2019
Entry Details Article
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422828BDBM50422828(TBR-652 | TAK-652 | CENICRIVIROC | CENICRIVIROC ME...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]MIP-3beta from CCR7 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50255479BDBM50255479(CHEMBL4067429)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CCR7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2019
Entry Details Article
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50463599BDBM50463599(CHEMBL4245355)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human CCR7 expressed in CHO cells assessed as decrease in CCL19-induced reduction of forskolin-stimulated cAMP accumulation preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666785BDBM50666785(CHEMBL6177821)
Affinity DataIC50: 2.94E+4nMAssay Description:Antagonist activity at human CCR7 expressed in HEK293T cells assessed as inhibition of CCL19 mediated Galpha-o activation using Nano-glo nanolucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50463582BDBM50463582(CHEMBL4245957)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CCR7 expressed in CHO cells assessed as decrease in CCL19-induced reduction of forskolin-stimulated cAMP accumulation preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50463583BDBM50463583(CHEMBL4242040)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CCR7 expressed in CHO cells assessed as decrease in CCL19-induced reduction of forskolin-stimulated cAMP accumulation preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50463592BDBM50463592(CHEMBL4245036)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CCR7 expressed in CHO cells assessed as decrease in CCL19-induced reduction of forskolin-stimulated cAMP accumulation preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 7(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50463578BDBM50463578(CHEMBL4250007)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CCR7 expressed in CHO cells assessed as decrease in CCL19-induced reduction of forskolin-stimulated cAMP accumulation preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed