Compile Data Set for Download or QSAR
Report error Found 302 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 9'
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113443BDBM50113443(CHEMBL3604484)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at CCR9 receptor (unknown origin) assessed as inhibition of TECK-induced calcium mobilization incubated for 10 mins prior to TECK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398334BDBM50398334(CHEMBL2178578)
Affinity DataKi:  1.10nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178705BDBM50178705(CHEMBL3814804)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at CCR9 (unknown origin) assessed as inhibition of TECK-stimulated calcium mobilization preincubated for 10 mins followed by agon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2017
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393502BDBM393502(US9969687, Compound 119)
Affinity DataKi:  2nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398334BDBM50398334(CHEMBL2178578)
Affinity DataIC50: 2.60nMAssay Description:Antagonist activity at recombinant human CCR9B expressed in BAF3 cells assessed as reduction in CCL25-induced chemotaxis preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398334BDBM50398334(CHEMBL2178578)
Affinity DataIC50: 2.80nMAssay Description:Antagonist activity at recombinant human CCR9A expressed in BAF3 cells assessed as reduction in CCL25-induced chemotaxis preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393520BDBM393520(US9969687, Compound 183)
Affinity DataKi:  3nMAssay Description:A calcium flux assay was used to determine the ability of the compounds to interfere with the binding between CCR9 and its chemokine ligand (TECK) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393520BDBM393520(US9969687, Compound 183)
Affinity DataKi:  3nMAssay Description:Antagonist activity at CCR9A receptor (unknown origin) overexpressed in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intrace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393561BDBM393561(US9969687, Compound 232)
Affinity DataKi:  3nMAssay Description:A calcium flux assay was used to determine the ability of the compounds to interfere with the binding between CCR9 and its chemokine ligand (TECK) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393502BDBM393502(US9969687, Compound 119)
Affinity DataKi:  3nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCl25-mediated cell migration preincubated for 30 mins followed C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393572BDBM393572(US9969687, Compound 244)
Affinity DataKi:  3nMAssay Description:A calcium flux assay was used to determine the ability of the compounds to interfere with the binding between CCR9 and its chemokine ligand (TECK) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393516BDBM393516(US9969687, Compound 175)
Affinity DataKi:  3nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393520BDBM393520(US9969687, Compound 183)
Affinity DataKi:  3nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113442BDBM50113442(CHEMBL3604485)
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at CCR9 receptor (unknown origin) assessed as inhibition of TECK-induced calcium mobilization incubated for 10 mins prior to TECK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113441BDBM50113441(CHEMBL3604486)
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at CCR9 receptor (unknown origin) assessed as inhibition of TECK-induced calcium mobilization incubated for 10 mins prior to TECK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398334BDBM50398334(CHEMBL2178578)
Affinity DataKi:  3.70nMAssay Description:Antagonist activity at CCR9A receptor (unknown origin) overexpressed in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intrace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113352BDBM50113352(CHEMBL3604487)
Affinity DataIC50: 3.80nMAssay Description:Antagonist activity at CCR9 receptor (unknown origin) assessed as inhibition of TECK-induced calcium mobilization incubated for 10 mins prior to TECK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393600BDBM393600(US9969687, Compound 281)
Affinity DataKi:  4nMAssay Description:A calcium flux assay was used to determine the ability of the compounds to interfere with the binding between CCR9 and its chemokine ligand (TECK) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113354BDBM50113354(CHEMBL3604489)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CCR9 receptor (unknown origin) assessed as inhibition of TECK-induced calcium mobilization incubated for 10 mins prior to TECK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393530BDBM393530(US9969687, Compound 194)
Affinity DataKi:  4nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393553BDBM393553(US9969687, Compound 224)
Affinity DataKi:  5nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398334BDBM50398334(CHEMBL2178578)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at CCR9 (unknown origin) assessed as inhibition of TECK-stimulated calcium mobilization preincubated for 10 mins followed by agon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393557BDBM393557(US9969687, Compound 228)
Affinity DataKi:  5nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393553BDBM393553(US9969687, Compound 224)
Affinity DataKi:  6nMAssay Description:A calcium flux assay was used to determine the ability of the compounds to interfere with the binding between CCR9 and its chemokine ligand (TECK) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393557BDBM393557(US9969687, Compound 228)
Affinity DataKi:  6nMAssay Description:Antagonist activity at CCR9A receptor (unknown origin) overexpressed in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intrace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393572BDBM393572(US9969687, Compound 244)
Affinity DataKi:  6nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393530BDBM393530(US9969687, Compound 194)
Affinity DataKi:  6nMAssay Description:Antagonist activity at CCR9A receptor (unknown origin) overexpressed in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intrace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393552BDBM393552(US9969687, Compound 222)
Affinity DataKi:  6nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398334BDBM50398334(CHEMBL2178578)
Affinity DataIC50: 6nMAssay Description:Binding affinity to CCR9More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393534BDBM393534(US9969687, Compound 199)
Affinity DataKi:  6nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393553BDBM393553(US9969687, Compound 224)
Affinity DataKi:  6nMAssay Description:Antagonist activity at CCR9A receptor (unknown origin) overexpressed in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intrace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393530BDBM393530(US9969687, Compound 194)
Affinity DataKi:  6nMAssay Description:A calcium flux assay was used to determine the ability of the compounds to interfere with the binding between CCR9 and its chemokine ligand (TECK) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393517BDBM393517(US9969687, Compound 176)
Affinity DataKi:  6nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113427BDBM50113427(CHEMBL3604496)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at CCR9 receptor (unknown origin) assessed as inhibition of TECK-induced calcium mobilization incubated for 10 mins prior to TECK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393557BDBM393557(US9969687, Compound 228)
Affinity DataKi:  6nMAssay Description:A calcium flux assay was used to determine the ability of the compounds to interfere with the binding between CCR9 and its chemokine ligand (TECK) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393559BDBM393559(US9969687, Compound 230)
Affinity DataKi:  6nMAssay Description:A calcium flux assay was used to determine the ability of the compounds to interfere with the binding between CCR9 and its chemokine ligand (TECK) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393569BDBM393569(US9969687, Compound 241)
Affinity DataKi:  7nMAssay Description:A calcium flux assay was used to determine the ability of the compounds to interfere with the binding between CCR9 and its chemokine ligand (TECK) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393522BDBM393522(US9969687, Compound 185)
Affinity DataKi:  7nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393549BDBM393549(US9969687, Compound 218)
Affinity DataKi:  7nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178714BDBM50178714(CHEMBL3814136)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at CCR9 (unknown origin) assessed as inhibition of TECK-stimulated calcium mobilization preincubated for 10 mins followed by agon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2017
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393559BDBM393559(US9969687, Compound 230)
Affinity DataKi:  8nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393536BDBM393536(US9969687, Compound 201)
Affinity DataKi:  8nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113440BDBM50113440(CHEMBL3604483)
Affinity DataIC50: 8.70nMAssay Description:Antagonist activity at CCR9 receptor (unknown origin) assessed as inhibition of TECK-induced calcium mobilization incubated for 10 mins prior to TECK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113358BDBM50113358(CHEMBL3604493)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at CCR9 receptor (unknown origin) assessed as inhibition of TECK-induced calcium mobilization incubated for 10 mins prior to TECK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393592BDBM393592(US9969687, Compound 271)
Affinity DataKi:  9nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393566BDBM393566(US9969687, Compound 237)
Affinity DataKi:  9nMAssay Description:A calcium flux assay was used to determine the ability of the compounds to interfere with the binding between CCR9 and its chemokine ligand (TECK) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393552BDBM393552(US9969687, Compound 222)
Affinity DataKi:  9nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCl25-mediated cell migration preincubated for 30 mins followed C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398334BDBM50398334(CHEMBL2178578)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at CCR9 receptor (unknown origin) assessed as inhibition of TECK-induced calcium mobilization incubated for 10 mins prior to TECK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393534BDBM393534(US9969687, Compound 199)
Affinity DataKi:  10nMAssay Description:Antagonist activity at CCR9A receptor (unknown origin) overexpressed in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intrace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 393534BDBM393534(US9969687, Compound 199)
Affinity DataKi:  10nMAssay Description:A calcium flux assay was used to determine the ability of the compounds to interfere with the binding between CCR9 and its chemokine ligand (TECK) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

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