Compile Data Set for Download or QSAR
Report error Found 140 Enz. Inhib. hit(s) with Target = 'Cathepsin E'
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM912(PEPSTATIN | Pepstatine | N-[(3-Methyl-1-oxobutyl)-...)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human recombinant cathepsin E using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50045284(2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propion...)
Affinity DataKi:  0.100nMAssay Description:Binding affinity against human cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM912(PEPSTATIN | Pepstatine | N-[(3-Methyl-1-oxobutyl)-...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of secreted cathepsin E in human MDA-MB-231 cells using Mca-Gly-Lys-Pro-Ile-Leu-PhePhe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate pretreated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM912(PEPSTATIN | Pepstatine | N-[(3-Methyl-1-oxobutyl)-...)
Affinity DataIC50: 0.181nMAssay Description:Inhibition of cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50382733(CHEMBL2024289)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM912(PEPSTATIN | Pepstatine | N-[(3-Methyl-1-oxobutyl)-...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged cathepsin E (Gln18 to Pro396 residues) using Mca-Gly-Lys-Pro-Ile-Leu-PhePhe-Arg-Leu-Lys-(Dnp)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50302109(Grassystatin B | CHEMBL568553)
Affinity DataIC50: 0.354nMAssay Description:Inhibition of cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50302109(Grassystatin B | CHEMBL568553)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged cathepsin E (Gln18 to Pro396 residues) using Mca-Gly-Lys-Pro-Ile-Leu-PhePhe-Arg-Leu-Lys-(Dnp)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50305527((4S)-4-[(1R)-1-hydroxy-2-({1-[3-(1-methylethyl)phe...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM912(PEPSTATIN | Pepstatine | N-[(3-Methyl-1-oxobutyl)-...)
Affinity DataIC50: 0.446nMAssay Description:Inhibition of Cathepsin E (unknown origin) using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate incubated for 120 mins by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM912(PEPSTATIN | Pepstatine | N-[(3-Methyl-1-oxobutyl)-...)
Affinity DataIC50: 0.446nMAssay Description:Inhibition of cathepsin E by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50008139(CHEMBL287423 | 2-[2-(Morpholine-4-sulfonylamino)-3...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity against human cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50283681(CHEMBL4163078)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged cathepsin E (Gln18 to Pro396 residues) using Mca-Gly-Lys-Pro-Ile-Leu-PhePhe-Arg-Leu-Lys-(Dnp)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50045290(2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propion...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity against human cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50400214(CHEMBL2181022)
Affinity DataIC50: 0.724nMAssay Description:Inhibition of Cathepsin E (unknown origin) using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate incubated for 120 mins by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50400214(CHEMBL2181022)
Affinity DataIC50: 0.724nMAssay Description:Inhibition of cathepsin E by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50302107(Grassystatin A | CHEMBL567893)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of cathepsin E by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50302107(Grassystatin A | CHEMBL567893)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of cathepsin E using MCA-KPILFFRLK(Dnp)-D-R-NH2 as substrate incubated for 10 to 15 mins prior to substrate addition measured every 5 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50302107(Grassystatin A | CHEMBL567893)
Affinity DataIC50: 0.886nMAssay Description:Inhibition of cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50302107(Grassystatin A | CHEMBL567893)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged cathepsin E (Gln18 to Pro396 residues) using Mca-Gly-Lys-Pro-Ile-Leu-PhePhe-Arg-Leu-Lys-(Dnp)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50400213(CHEMBL2181024)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of cathepsin E by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50045281(2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propion...)
Affinity DataKi:  2nMAssay Description:Binding affinity against human cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50271627(N'-[(1S,2S)-2-[(4S)-1-benzyl-5-oxoimidazolidin-4-y...)
Affinity DataKi:  2nMAssay Description:Inhibition of cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50045285(2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propion...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity against human cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50045287(N-[Allylsulfanyl-(1-cyclohexylmethyl-2,4-dihydroxy...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity against human cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50281636((S)-N*1*-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataKi:  3nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to Cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50045283(2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propion...)
Affinity DataKi:  3.30nMAssay Description:Binding affinity against human cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50305537((S)-4-{(R)-1-Hydroxy-2-[1-(3-isopropyl-phenyl)-cyc...)
Affinity DataIC50: 4nMAssay Description:Inhibition of cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50400215(CHEMBL2181021)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of cathepsin E by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50372198(CHEMBL270359)
Affinity DataKi:  5nMAssay Description:Inhibition of cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50372198(CHEMBL270359)
Affinity DataKi:  5nMAssay Description:Binding affinity to human cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50283686(CHEMBL4170992)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged cathepsin E (Gln18 to Pro396 residues) using Mca-Gly-Lys-Pro-Ile-Leu-PhePhe-Arg-Leu-Lys-(Dnp)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50305536((S)-4-{(R)-1-Hydroxy-2-[1-(3-isopropyl-phenyl)-cyc...)
Affinity DataIC50: 5nMAssay Description:Inhibition of cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM912(PEPSTATIN | Pepstatine | N-[(3-Methyl-1-oxobutyl)-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of cathepsin E in human MCF7 cells by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM912(PEPSTATIN | Pepstatine | N-[(3-Methyl-1-oxobutyl)-...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of cathepsin E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50305533((S)-4-[(R)-1-Hydroxy-2-(3-isopropyl-benzylamino)-e...)
Affinity DataIC50: 8nMAssay Description:Inhibition of cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50400221(CHEMBL2181015)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant cathepsin E using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50283684(CHEMBL4167618)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged cathepsin E (Gln18 to Pro396 residues) using Mca-Gly-Lys-Pro-Ile-Leu-PhePhe-Arg-Leu-Lys-(Dnp)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50045282(2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propion...)
Affinity DataKi:  11nMAssay Description:Binding affinity against human cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50603526(CHEMBL5184529)
Affinity DataIC50: 12nMAssay Description:Inhibition of Cathepsin E (unknown origin) using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate incubated for 120 mins by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50045289(6-(3-Methyl-thioureido)-2-[2-(morpholine-4-sulfony...)
Affinity DataKi:  15nMAssay Description:Binding affinity against human cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50045292(2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propion...)
Affinity DataKi:  17nMAssay Description:Binding affinity against human cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50400218(CHEMBL2181018)
Affinity DataIC50: 21nMAssay Description:Inhibition of cathepsin E by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50045291(i2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propio...)
Affinity DataKi:  21nMAssay Description:Binding affinity against human cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50178261(CHEMBL3813928)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant cathepsin E using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50283685(CHEMBL4159706)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged cathepsin E (Gln18 to Pro396 residues) using Mca-Gly-Lys-Pro-Ile-Leu-PhePhe-Arg-Leu-Lys-(Dnp)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50372181(CHEMBL403727)
Affinity DataKi:  24nMAssay Description:Binding affinity to human cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50372181(CHEMBL403727)
Affinity DataKi:  24nMAssay Description:Inhibition of cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50400217(CHEMBL2181019)
Affinity DataIC50: 30nMAssay Description:Inhibition of cathepsin E by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50283683(CHEMBL4173516)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged cathepsin E (Gln18 to Pro396 residues) using Mca-Gly-Lys-Pro-Ile-Leu-PhePhe-Arg-Leu-Lys-(Dnp)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
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