Compile Data Set for Download or QSAR
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Found 48 Enz. Inhib. hit(s) with Target = 'Chitin synthase 1'
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50559071(CHEMBL4741395)
Affinity DataKi:  0.550nMAssay Description:Inhibition of Candida albicans chitin synthase 1 expressed in Saccharomyces cerevisiae RRA400-1U cells using [3H]UDP-GlcNAc as substrate by scintilla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50367322(CHEMBL1791178)
Affinity DataKi:  590nMAssay Description:Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50559072(CHEMBL4786444)
Affinity DataKi:  630nMAssay Description:Inhibition of Candida albicans chitin synthase 1 expressed in Saccharomyces cerevisiae RRA400-1U cells using [3H]UDP-GlcNAc as substrate by scintilla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50367323(CHEMBL1791436)
Affinity DataKi:  7.15E+3nMAssay Description:Compound was tested for the inhibitory activity against chitin synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50367324(CHEMBL1791438)
Affinity DataKi:  1.13E+4nMAssay Description:Compound was tested for the inhibitory activity against chitin synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50367327(CHEMBL1791441)
Affinity DataKi:  1.45E+5nMAssay Description:Compound was tested for the inhibitory activity against chitin synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50367325(CHEMBL1791435)
Affinity DataKi:  2.18E+5nMAssay Description:Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50367326(CHEMBL1791440)
Affinity DataKi:  2.46E+5nMAssay Description:Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50367320(CHEMBL1791437)
Affinity DataKi:  9.78E+5nMAssay Description:Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50367321(CHEMBL1791439)
Affinity DataKi:  1.06E+6nMAssay Description:Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089536(5-[(6,6-Dimethyl-hepta-2,4-diynyl)-methyl-amino]-3...)
Affinity DataIC50:  0.140nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Saccharomyces cerevisiae)
Universidad Nacional De Rosario

Curated by ChEMBL
LigandPNGBDBM50089541((R)-[(S)-(2S,3S,4S)-2-Amino-4-hydroxy-4-(5-hydroxy...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of chitin synthase 1 in Saccharomyces cerevisiae after 90 mins in presence of trypsinMore data for this Ligand-Target Pair
TargetChitin synthase 1(Saccharomyces cerevisiae)
Universidad Nacional De Rosario

Curated by ChEMBL
LigandPNGBDBM50089541((R)-[(S)-(2S,3S,4S)-2-Amino-4-hydroxy-4-(5-hydroxy...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of chitin synthase 1 in Saccharomyces cerevisiae assessed as incorporation of [14C]-N-Acetylglucosamine after 90 minsMore data for this Ligand-Target Pair
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089557(5-[Butyl-((E)-6,6-dimethyl-hept-2-en-4-ynyl)-amino...)
Affinity DataIC50:  0.350nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089551(5-[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-propyl-amin...)
Affinity DataIC50:  0.680nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089540(CHEMBL32125 | Phosphoric acid 5-[(6,6-dimethyl-hep...)
Affinity DataIC50:  0.760nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089563(5-[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-amino...)
Affinity DataIC50:  0.900nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089538(5-[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-pentyl-amin...)
Affinity DataIC50:  1.10nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089559(5-[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-isopropyl-a...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089543(5-[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-methyl-amin...)
Affinity DataIC50:  2.80nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089547(5-[(6,6-Dimethyl-hepta-2,4-diynyl)-methyl-amino]-3...)
Affinity DataIC50:  3nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089537(5-{[4-(3,3-Dimethyl-but-1-ynyl)-benzyl]-methyl-ami...)
Affinity DataIC50:  7.20nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089560(5-(Hepta-2,4-diynyl-methyl-amino)-3,4-dihydro-1H-q...)
Affinity DataIC50:  7.90nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089550(5-[(6,6-Dimethyl-hept-4-ynyl)-methyl-amino]-3,4-di...)
Affinity DataIC50:  9nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089562(3-Amino-5-[(6,6-dimethyl-hepta-2,4-diynyl)-methyl-...)
Affinity DataIC50:  12nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089561(5-[((Z)-6,6-Dimethyl-hept-2-en-4-ynyl)-methyl-amin...)
Affinity DataIC50:  13nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089535((R)-2-Amino-3-methyl-butyric acid 5-[(6,6-dimethyl...)
Affinity DataIC50:  15nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089556(5-[Benzyl-((E)-6,6-dimethyl-hept-2-en-4-ynyl)-amin...)
Affinity DataIC50:  54nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089546(5-((E)-6,6-Dimethyl-hept-2-en-4-ynylamino)-1H-quin...)
Affinity DataIC50:  70nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089546(5-((E)-6,6-Dimethyl-hept-2-en-4-ynylamino)-1H-quin...)
Affinity DataIC50:  71nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089548(5-((E)-6,6-Dimethyl-hept-2-en-4-ynylamino)-3,4-dih...)
Affinity DataIC50:  71nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089558(5-[(6-Hydroxy-6-methyl-hepta-2,4-diynyl)-methyl-am...)
Affinity DataIC50:  213nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089553(CHEMBL32687 | N-((E)-6,6-Dimethyl-hept-2-en-4-ynyl...)
Affinity DataIC50:  391nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Saccharomyces cerevisiae)
Universidad Nacional De Rosario

Curated by ChEMBL
LigandPNGBDBM50231813((2S,4aR,6aS,6bR,8aR,9R,10R,11S,12aR,12bR,14bS)-11-...)
Affinity DataIC50: >400nMAssay Description:Inhibition of chitin synthase 1 in Saccharomyces cerevisiae assessed as incorporation of [14C]N-Acetylglucosamine after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Saccharomyces cerevisiae)
Universidad Nacional De Rosario

Curated by ChEMBL
LigandPNGBDBM50231813((2S,4aR,6aS,6bR,8aR,9R,10R,11S,12aR,12bR,14bS)-11-...)
Affinity DataIC50: >400nMAssay Description:Inhibition of chitin synthase 1 in Saccharomyces cerevisiae assessed as incorporation of [14C]-N-Acetylglucosamine after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089552(CHEMBL416596 | N-((E)-6,6-Dimethyl-hept-2-en-4-yny...)
Affinity DataIC50:  775nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089554(CHEMBL35365 | N-[3-((E)-6,6-Dimethyl-hept-2-en-4-y...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089555(5-[(6-Methoxy-6-methyl-hepta-2,4-diynyl)-methyl-am...)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089541((R)-[(S)-(2S,3S,4S)-2-Amino-4-hydroxy-4-(5-hydroxy...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089541((R)-[(S)-(2S,3S,4S)-2-Amino-4-hydroxy-4-(5-hydroxy...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089545(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-quinolin-5-yl-...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089539(5-((E)-6,6-Dimethyl-hept-2-en-4-ynylamino)-chromen...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089549(5-[Methyl-(5-phenyl-penta-2,4-diynyl)-amino]-3,4-d...)
Affinity DataIC50:  1.37E+4nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089542(5-((E)-6,6-Dimethyl-hept-2-en-4-ynylamino)-1-methy...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1/2/3(Candida albicans)TBA
LigandPNGBDBM50089537(5-{[4-(3,3-Dimethyl-but-1-ynyl)-benzyl]-methyl-ami...)
Affinity DataIC50:  2.08E+4nMAssay Description:Inhibition of Candida albicans chitin synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50559070(CHEMBL1182094)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of Chitin synthase 1 in Candida albicans (chs3del::hisG/chs3del::hisG) microsomes using UDP-[U14C]-GlcNac as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089564(5-[((E)-6,6-Dimethyl-hept-2-en-4-ynylamino)-methyl...)
Affinity DataIC50:  2.11E+5nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Candida albicans)
Shaanxi University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50089544(5-(6,6-Dimethyl-heptylamino)-1H-quinolin-2-one | C...)
Affinity DataIC50: >3.50E+5nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed