Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with Target = 'Chitin synthase 1'
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089536BDBM50089536(5-[(6,6-Dimethyl-hepta-2,4-diynyl)-methyl-amino]-3...)
Affinity DataIC50: 0.140nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Baker's yeast)
Universidad Nacional De Rosario

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089541BDBM50089541((S)-[(2S,3S,4S)-2-Amino-4-hydroxy-4-(5-hydroxy-pyr...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of chitin synthase 1 in Saccharomyces cerevisiae after 90 mins in presence of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetChitin synthase 1(Baker's yeast)
Universidad Nacional De Rosario

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089541BDBM50089541((S)-[(2S,3S,4S)-2-Amino-4-hydroxy-4-(5-hydroxy-pyr...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of chitin synthase 1 in Saccharomyces cerevisiae assessed as incorporation of [14C]-N-Acetylglucosamine after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089557BDBM50089557(5-[Butyl-((E)-6,6-dimethyl-hept-2-en-4-ynyl)-amino...)
Affinity DataIC50: 0.350nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559071BDBM50559071(CHEMBL4741395)
Affinity DataKi:  0.550nMAssay Description:Inhibition of Candida albicans chitin synthase 1 expressed in Saccharomyces cerevisiae RRA400-1U cells using [3H]UDP-GlcNAc as substrate by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089551BDBM50089551(5-[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-propyl-amin...)
Affinity DataIC50: 0.680nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089540BDBM50089540(Phosphoric acid 5-[(6,6-dimethyl-hepta-2,4-diynyl)...)
Affinity DataIC50: 0.760nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089563BDBM50089563(5-[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-amino...)
Affinity DataIC50: 0.900nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089538BDBM50089538(5-[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-pentyl-amin...)
Affinity DataIC50: 1.10nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089559BDBM50089559(5-[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-isopropyl-a...)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089543BDBM50089543(5-[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-methyl-amin...)
Affinity DataIC50: 2.80nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089547BDBM50089547(5-[(6,6-Dimethyl-hepta-2,4-diynyl)-methyl-amino]-3...)
Affinity DataIC50: 3nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089537BDBM50089537(5-{[4-(3,3-Dimethyl-but-1-ynyl)-benzyl]-methyl-ami...)
Affinity DataIC50: 7.20nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089560BDBM50089560(5-(Hepta-2,4-diynyl-methyl-amino)-3,4-dihydro-1H-q...)
Affinity DataIC50: 7.90nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089550BDBM50089550(5-[(6,6-Dimethyl-hept-4-ynyl)-methyl-amino]-3,4-di...)
Affinity DataIC50: 9nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089562BDBM50089562(3-Amino-5-[(6,6-dimethyl-hepta-2,4-diynyl)-methyl-...)
Affinity DataIC50: 12nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089561BDBM50089561(5-[((Z)-6,6-Dimethyl-hept-2-en-4-ynyl)-methyl-amin...)
Affinity DataIC50: 13nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089535BDBM50089535((R)-2-Amino-3-methyl-butyric acid 5-[(6,6-dimethyl...)
Affinity DataIC50: 15nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089556BDBM50089556(5-[Benzyl-((E)-6,6-dimethyl-hept-2-en-4-ynyl)-amin...)
Affinity DataIC50: 54nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089546BDBM50089546(5-((E)-6,6-Dimethyl-hept-2-en-4-ynylamino)-1H-quin...)
Affinity DataIC50: 70nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089546BDBM50089546(5-((E)-6,6-Dimethyl-hept-2-en-4-ynylamino)-1H-quin...)
Affinity DataIC50: 71nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089548BDBM50089548(5-((E)-6,6-Dimethyl-hept-2-en-4-ynylamino)-3,4-dih...)
Affinity DataIC50: 71nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089558BDBM50089558(5-[(6-Hydroxy-6-methyl-hepta-2,4-diynyl)-methyl-am...)
Affinity DataIC50: 213nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089553BDBM50089553(N-((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-N-(2-oxo-1,2...)
Affinity DataIC50: 391nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Baker's yeast)
Universidad Nacional De Rosario

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231813BDBM50231813(3-O-beta-D-xylopiranosylphytolaccagenin | (2S,4aR,...)
Affinity DataIC50: 400nMAssay Description:Inhibition of chitin synthase 1 in Saccharomyces cerevisiae assessed as incorporation of [14C]-N-Acetylglucosamine after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetChitin synthase 1(Baker's yeast)
Universidad Nacional De Rosario

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231813BDBM50231813(3-O-beta-D-xylopiranosylphytolaccagenin | (2S,4aR,...)
Affinity DataIC50: 400nMAssay Description:Inhibition of chitin synthase 1 in Saccharomyces cerevisiae assessed as incorporation of [14C]N-Acetylglucosamine after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367322BDBM50367322(CHEMBL1791178)
Affinity DataKi:  590nMAssay Description:Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559072BDBM50559072(CHEMBL4786444)
Affinity DataKi:  630nMAssay Description:Inhibition of Candida albicans chitin synthase 1 expressed in Saccharomyces cerevisiae RRA400-1U cells using [3H]UDP-GlcNAc as substrate by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089552BDBM50089552(N-((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-N-(2-oxo-1,2...)
Affinity DataIC50: 775nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089554BDBM50089554(N-[3-((E)-6,6-Dimethyl-hept-2-en-4-ynylamino)-phen...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089555BDBM50089555(5-[(6-Methoxy-6-methyl-hepta-2,4-diynyl)-methyl-am...)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089541BDBM50089541((S)-[(2S,3S,4S)-2-Amino-4-hydroxy-4-(5-hydroxy-pyr...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089541BDBM50089541((S)-[(2S,3S,4S)-2-Amino-4-hydroxy-4-(5-hydroxy-pyr...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089545BDBM50089545(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-quinolin-5-yl-...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367323BDBM50367323(CHEMBL1791436)
Affinity DataKi:  7.15E+3nMAssay Description:Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367324BDBM50367324(CHEMBL1791438)
Affinity DataKi:  1.13E+4nMAssay Description:Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089539BDBM50089539(5-((E)-6,6-Dimethyl-hept-2-en-4-ynylamino)-chromen...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089549BDBM50089549(5-[Methyl-(5-phenyl-penta-2,4-diynyl)-amino]-3,4-d...)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089542BDBM50089542(5-((E)-6,6-Dimethyl-hept-2-en-4-ynylamino)-1-methy...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1/2/3(Yeast)TBA
LigandChemical structure of BindingDB Monomer ID 50089537BDBM50089537(5-{[4-(3,3-Dimethyl-but-1-ynyl)-benzyl]-methyl-ami...)
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of Candida albicans chitin synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559070BDBM50559070(CHEMBL1182094)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of Chitin synthase 1 in Candida albicans (chs3del::hisG/chs3del::hisG) microsomes using UDP-[U14C]-GlcNac as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367327BDBM50367327(CHEMBL1791441)
Affinity DataKi:  1.45E+5nMAssay Description:Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089564BDBM50089564(5-[((E)-6,6-Dimethyl-hept-2-en-4-ynylamino)-methyl...)
Affinity DataIC50: 2.11E+5nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367325BDBM50367325(CHEMBL1791435)
Affinity DataKi:  2.18E+5nMAssay Description:Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367326BDBM50367326(CHEMBL1791440)
Affinity DataKi:  2.46E+5nMAssay Description:Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089544BDBM50089544(5-(6,6-Dimethyl-heptylamino)-1H-quinolin-2-one | C...)
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367320BDBM50367320(CHEMBL1791437)
Affinity DataKi:  9.78E+5nMAssay Description:Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetChitin synthase 1(Yeast)
Nippon Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367321BDBM50367321(CHEMBL1791439)
Affinity DataKi:  1.06E+6nMAssay Description:Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed