Compile Data Set for Download or QSAR
Report error Found 1080 Enz. Inhib. hit(s) with Target = 'Chymase'
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520051BDBM50520051(CHEMBL4592765)
Affinity DataKi:  0.220nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 100340BDBM100340(US8501749, 40)
Affinity DataIC50: 0.300nMpH: 8.0 T: 2°CAssay Description:In vitro inhibition assay of Chymase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
US Patent

TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 100336BDBM100336(US8501749, 36)
Affinity DataIC50: 0.400nMpH: 8.0 T: 2°CAssay Description:In vitro inhibition assay of Chymase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
US Patent

TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332961BDBM50332961((3S,4S)-3-Benzyl-4-(4-methylpiperazincarbonyl)phen...)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human ChymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 100335BDBM100335(US8501749, 35)
Affinity DataIC50: 0.700nMpH: 8.0 T: 2°CAssay Description:In vitro inhibition assay of Chymase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
US Patent

TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 100338BDBM100338(US8501749, 38)
Affinity DataIC50: 0.700nMpH: 8.0 T: 2°CAssay Description:In vitro inhibition assay of Chymase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
US Patent

TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101136BDBM50101136(1,3-Bis-benzo[1,3]dioxol-5-ylmethyl-[1,3]diazetidi...)
Affinity DataIC50: 0.850nMAssay Description:Compound was evaluated for its inhibitory activity against human Serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 100324BDBM100324(US8501749, 24)
Affinity DataIC50: 0.900nMpH: 8.0 T: 2°CAssay Description:In vitro inhibition assay of Chymase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 255962BDBM255962(US9481672, 140)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 256099BDBM256099(US9481672, 281)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 256036BDBM256036(US9481672, 217)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 256065BDBM256065(US9481672, 247)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 255968BDBM255968(US9481672, 146)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 256064BDBM256064(US9481672, 246)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 255964BDBM255964(US9481672, 142)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098853BDBM50098853(2-(2-{2-[5-Amino-2-(3-methoxy-phenyl)-6-oxo-6H-pyr...)
Affinity DataKi:  1.12nMAssay Description:Inhibitory activity against canine skin chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068901BDBM50068901(3-[2,2-Difluoro-4-({(S)-1-[(S)-3-methyl-2-(3-pheny...)
Affinity DataKi:  1.30nMAssay Description:Compound was evaluated for inhibitory activity against human heart chymase (HHC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 100341BDBM100341(US8501749, 41)
Affinity DataIC50: 1.30nMpH: 8.0 T: 2°CAssay Description:In vitro inhibition assay of Chymase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
US Patent

TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 100330BDBM100330(US8501749, 30)
Affinity DataIC50: 1.40nMpH: 8.0 T: 2°CAssay Description:In vitro inhibition assay of Chymase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
US Patent

TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 100339BDBM100339(US8501749, 39)
Affinity DataIC50: 1.40nMpH: 8.0 T: 2°CAssay Description:In vitro inhibition assay of Chymase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
US Patent

TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520048BDBM50520048(CHEMBL4450993)
Affinity DataKi:  1.70nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 88376BDBM88376(US9695131, 13)
Affinity DataIC50: 1.80nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2018
Entry Details
US Patent

TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520049BDBM50520049(CHEMBL4560112)
Affinity DataKi:  1.80nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 255944BDBM255944(US9481672, 122)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 255973BDBM255973(US9481672, 151)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 255971BDBM255971(US9481672, 149)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 255954BDBM255954(US9481672, 132)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 256111BDBM256111(US9481672, 294)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 256046BDBM256046(US9481672, 227)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 256043BDBM256043(US9481672, 224)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 255961BDBM255961(US9481672, 139)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 255927BDBM255927(US9481672, 104)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 255958BDBM255958(US9481672, 136)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 256083BDBM256083(US9481672, 265)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 255956BDBM255956(US9481672, 134)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 256116BDBM256116(US9481672, 300)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 255969BDBM255969(US9481672, 147)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101135BDBM50101135(1,3-Bis-(4-methoxy-benzyl)-[1,3]diazetidine-2,4-di...)
Affinity DataIC50: 2nMAssay Description:Compound was evaluated for its inhibitory activity against human Serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 256066BDBM256066(US9481672, 248)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 255967BDBM255967(US9481672, 145)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 256095BDBM256095(US9481672, 277)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 255965BDBM255965(US9481672, 143)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 255966BDBM255966(US9481672, 144)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 256062BDBM256062(US9481672, 244)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 255963BDBM255963(US9481672, 141)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 256059BDBM256059(US9481672, 241)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 256088BDBM256088(BDBM256092 | BDBM256093 | US9481672, 270)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 100320BDBM100320(US8501749, 20)
Affinity DataIC50: 2.10nMpH: 8.0 T: 2°CAssay Description:In vitro inhibition assay of Chymase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
US Patent

TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520060BDBM50520060(CHEMBL4465306)
Affinity DataKi:  2.20nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 100331BDBM100331(US8501749, 31)
Affinity DataIC50: 2.20nMpH: 8.0 T: 2°CAssay Description:In vitro inhibition assay of Chymase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
US Patent

Displayed 1 to 50 (of 1080 total ) | Next | Last >>
Jump to: