Compile Data Set for Download or QSAR
Report error Found 203 Enz. Inhib. hit(s) with Target = 'Chymotrypsinogen B'
TargetChymotrypsinogen B2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520048(CHEMBL4450993)
Affinity DataKi:  0.420nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymotrypsinogen B2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520063(CHEMBL4586444)
Affinity DataKi:  0.880nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymotrypsinogen B2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520058(CHEMBL4469390)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50: 1.60nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50: 1.60nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073139([2,2-dimethyl-3-(N-(4-cyanobenzoyl)aminoi)-5-pheny...)
Affinity DataIC50: 2.10nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073139([2,2-dimethyl-3-(N-(4-cyanobenzoyl)aminoi)-5-pheny...)
Affinity DataIC50: 2.10nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50: 2.60nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075109(1,1-dimethyl-2-phenylcarboxamidoheptanoic anhydrid...)
Affinity DataIC50: 5.30nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50024092(6-Iodomethylene-4-phenyl-tetrahydro-pyran-2-one | ...)
Affinity DataKi:  5.30nMAssay Description:Binding constant alpha-chymotrypsin was determined by competitive inhibition assay with Suc-Ala-Ala-Pro-Phe-pNA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50142284(2-Ethyl-1,1-dioxo-1,2,3,4,6,7-hexahydro-5,8-dioxa-...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against chymotrypsinogen; Range 1-10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetChymotrypsinogen B2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520064(CHEMBL4590739)
Affinity DataKi:  11nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075107(1,1-dimethyl-4-phenyl-2-propylcarboxamidopentanoic...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075107(1,1-dimethyl-4-phenyl-2-propylcarboxamidopentanoic...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50437999(CHEMBL2409452)
Affinity DataIC50: 15nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075110(2-(4-cyanophenylcarboxamido)-1,1-dimethyl-2-phenyl...)
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50014743(CHEMBL132171 | N-(1-{2-[2-(1-Benzyl-3,3,3-trifluor...)
Affinity DataKi:  17nMAssay Description:Binding affinity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075106(1,1-dimethyl-4-phenyl-2-phenylcarboxamidopentanoic...)
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075106(1,1-dimethyl-4-phenyl-2-phenylcarboxamidopentanoic...)
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)
Affinity DataKi:  20nMAssay Description:Inhibition of human chymotrypsin by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50437997(CHEMBL2409457)
Affinity DataIC50: 21nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50438000(CHEMBL2409451)
Affinity DataIC50: 31nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075114(1,1-dimethyl-2-phenylcarboxamidooctanoic anhydride...)
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM247411(US9453018, 353 | US10336754, Example 353 | US11053...)
Affinity DataKi:  35nMAssay Description:Binding affinity to human chymotrypsin assessed as inhibition constant using 3-Carbomethoxypropionyl-L-arginyl-Lprolyl-L-tyrosine p-Nitroaniline as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50437992(CHEMBL2409445)
Affinity DataIC50: 38nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50437998(CHEMBL2409456)
Affinity DataIC50: 40nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075104(1,1-dimethyl-2-phenylcarboxamidononanoic anhydride...)
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50437996(CHEMBL2409458)
Affinity DataIC50: 46nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075118(1,1-dimethyl-2-phenylcarboxamidohexanoic anhydride...)
Affinity DataIC50: 49nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50289952(6-Dimethylamino-5-methyl-2-(1-phenyl-ethylamino)-b...)
Affinity DataIC50: 65nMAssay Description:Inhibitory concentration against human chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50437991(CHEMBL2409450)
Affinity DataIC50: 66nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075105(1,1-dimethyl-2-phenylcarboxamidopentanoic anhydrid...)
Affinity DataIC50: 72nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50014731(CHEMBL130006 | 3-[(1-{2-[2-(3-Methoxycarbonyl-prop...)
Affinity DataKi:  79nMAssay Description:Binding affinity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073127((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50: 86nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50289954(5-Methyl-2-(1-phenyl-ethylamino)-benzo[d][1,3]oxaz...)
Affinity DataIC50: 88nMAssay Description:Inhibitory concentration against human chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50437994(CHEMBL2409571)
Affinity DataIC50: 140nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075113(1,1-dimethyl-2-phenylcarboxamidopropanoic anhydrid...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50289953(2-[1-(4-Bromo-phenyl)-ethylamino]-5-methyl-benzo[d...)
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration against human chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetChymotrypsinogen B2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520051(CHEMBL4592765)
Affinity DataKi:  150nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50437995(CHEMBL2409570)
Affinity DataIC50: 170nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50289955(5-Methyl-2-(1-phenyl-ethylamino)-benzo[d][1,3]oxaz...)
Affinity DataIC50: 180nMAssay Description:Inhibitory concentration against human chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075116(2-(4-cyanophenylcarboxamido)-1,1-dimethyl-2-(2-met...)
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075111(2-(4-cyanophenylcarboxamido)-2-cyclohex-3-enyl-1,1...)
Affinity DataIC50: 220nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073126((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50: 230nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073141((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-5-phe...)
Affinity DataIC50: 250nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075108(2-(2-chlorophenyl)-2-(4-cyanophenylcarboxamido)-1,...)
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50025866(N-[1R-(2-phenyl ethyl)]benzamide difluoroborane | ...)
Affinity DataKi:  270nMAssay Description:Competitive inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50025877(N-[1R-(2-phenyl ethyl)]propanamide difluoroborane ...)
Affinity DataKi:  290nMAssay Description:Competitive inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50069989(CHEMBL325041 | (R)-3-methyl-1-((S)-3-phenyl-2-(pyr...)
Affinity DataKi:  320nMAssay Description:Inhibitory activity against human ChymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50025875(2-Amino-N-[1R-(2-phenyl ethyl)]propanamide boronic...)
Affinity DataKi:  320nMAssay Description:Competitive inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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