Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with Target = 'Coagulation factor XIII A chain [Q652E]'
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608714BDBM50608714(CHEMBL5281897)
Affinity DataIC50: 26nMAssay Description:Inhibition of human plasma coagulation factor XIIIa by fluorescence spectrophotometeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608719BDBM50608719(CHEMBL5269766)
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant coagulation factor XIIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50164227BDBM50164227(5-Methyl-2-(2-oxo-propylsulfanyl)-thiazolo[2,3-b][...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human plasma coagulation factor XIIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608720BDBM50608720(CHEMBL5285085)
Affinity DataIC50: 102nMAssay Description:Inhibition of human recombinant coagulation factor XIIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 577548BDBM577548(US11472838, Compound Ref. 22)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant coagulation factor XIIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608718BDBM50608718(CHEMBL5286758)
Affinity DataIC50: 139nMAssay Description:Inhibition of human recombinant coagulation factor XIIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136842BDBM50136842(N-[2-(4-hydroxyphenyl)ethylacetamide | N-[2-(4-Hyd...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human coagulation factor XIIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608713BDBM50608713(CHEMBL5275210)
Affinity DataIC50: 310nMAssay Description:Inhibition of human plasma coagulation factor XIIIa by fluorescence spectrophotometeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608710BDBM50608710(CHEMBL5290263)
Affinity DataIC50: 350nMAssay Description:Inhibition of human plasma coagulation factor XIIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608712BDBM50608712(CHEMBL5286863)
Affinity DataIC50: 610nMAssay Description:Inhibition of human plasma coagulation factor XIIIa by fluorescence spectrophotometeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608711BDBM50608711(CHEMBL5290280)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human plasma coagulation factor XIIIa by fluorescence spectrophotometeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608715BDBM50608715(CHEMBL5273935)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human recombinant coagulation factor XIIIa incubated for 55 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608716BDBM50608716(CHEMBL5269322)
Affinity DataKd:  2.53E+4nMAssay Description:Binding affinity to human coagulation factor XIIIa by Spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608716BDBM50608716(CHEMBL5269322)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of human coagulation factor XIIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 185173BDBM185173(N-[2-[4-(adamantane-1-carbonyl)piperazin-1-yl]-2-o...)
Affinity DataIC50: 3.70E+4nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608716BDBM50608716(CHEMBL5269322)
Affinity DataIC50: 7.63E+4nMAssay Description:Inhibition of human coagulation factor XIIIa assessed as inhibition of factor 13a mediated fibrin polymerization incubated for 24 hrs by SDS-PAGE ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 185182BDBM185182([2-[[2-[4-[[5-(Dimethylamino)-1-naphthyl]sulfonyl]...)
Affinity DataIC50: 1.00E+5nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 185181BDBM185181(N-[2-[4-[[5-(dimethylamino)-1-naphthyl]sulfonyl]pi...)
Affinity DataIC50: 1.00E+5nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009353BDBM50009353(spermidine | 4-azaoctane-1,8-diamine | 4-azaoctame...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human coagulation factor XIIIa assessed as inhibition of factor 13a mediated crosslinking of fibronectin-collagen incubated for 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 79403BDBM79403(N,N''-bis(3-azanylpropyl)butane-1,4-diamine;hydroc...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human coagulation factor XIIIa assessed as inhibition of factor 13a mediated crosslinking of fibronectin-collagen incubated for 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 185161BDBM185161(Dimethyl-[2-[[2-[4-(2-naphthylmethoxycarbonyl)pipe...)
Affinity DataIC50: 1.00E+5nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 185155BDBM185155([2-[[2-(4-Benzyloxycarbonylpiperazin-1-yl)-2-oxo-e...)
Affinity DataIC50: 1.00E+5nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 185170BDBM185170(N-[2-[4-(adamantane-1-carbonyl)piperazin-1-yl]-2-o...)
Affinity DataIC50: 1.00E+5nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 185168BDBM185168([2-[[2-[4-[(4-Methoxycarbonylphenyl)methoxycarbony...)
Affinity DataIC50: 1.00E+5nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 185183BDBM185183(2-(1-Adamantyl)ethyl 4-[2-[(2-bromoacetyl)amino]ac...)
Affinity DataIC50: 1.00E+5nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 185172BDBM185172([2-[[2-[4-(Adamantane-1-carbonyl)piperazin-1-yl]-2...)
Affinity DataIC50: 1.00E+5nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 185163BDBM185163((6-Methoxycarbonyl-2-naphthyl)methyl 4-[2-[(2-brom...)
Affinity DataIC50: 1.00E+5nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 185162BDBM185162(2-Naphthylmethyl 4-[2-(prop-2-enoylamino)acetyl]pi...)
Affinity DataIC50: 1.00E+5nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 185164BDBM185164((6-Methoxycarbonyl-2-naphthyl)methyl 4-[2-(prop-2-...)
Affinity DataIC50: 1.00E+5nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60581BDBM60581([2-[[2-[4-[(6-Methoxycarbonyl-2-naphthyl)methoxyca...)
Affinity DataIC50: 1.00E+5nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 185177BDBM185177(1-Adamantylmethyl 4-[2-(prop-2-enoylamino)acetyl]p...)
Affinity DataIC50: 1.00E+5nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 185176BDBM185176([2-[[2-[4-(1-Adamantylmethoxycarbonyl)piperazin-1-...)
Affinity DataIC50: 1.00E+5nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 185180BDBM185180([2-[[2-(4-tert-Butoxycarbonylpiperazin-1-yl)-2-oxo...)
Affinity DataIC50: 1.00E+5nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 185179BDBM185179(2-(1-Adamantyl)ethyl 4-[2-(prop-2-enoylamino)acety...)
Affinity DataIC50: 1.00E+5nMAssay Description:For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608717BDBM50608717(CHEMBL5273326)
Affinity DataIC50: 1.18E+5nMAssay Description:Inhibition of human coagulation factor XIIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed