Compile Data Set for Download or QSAR
Report error Found 888 Enz. Inhib. hit(s) with Target = 'Cyclin-C'
TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandChemical structure of BindingDB Monomer ID 350239BDBM350239(US10208056, Compound 66)
Affinity DataIC50: 0.191nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248627BDBM50248627(CHEMBL4078454)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of full length recombinant human His-tagged CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandChemical structure of BindingDB Monomer ID 350249BDBM350249(US10208056, Compound 76)
Affinity DataIC50: 0.262nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandChemical structure of BindingDB Monomer ID 350256BDBM350256(US10208056, Compound 83)
Affinity DataIC50: 0.278nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandChemical structure of BindingDB Monomer ID 350253BDBM350253(US10208056, Compound 80)
Affinity DataIC50: 0.314nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248633BDBM50248633(CHEMBL4083552)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248645BDBM50248645(CHEMBL4061525)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632902BDBM50632902(CHEMBL5435821)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248623BDBM50248623(CHEMBL4096487)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of full length recombinant human His-tagged CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632908BDBM50632908(CHEMBL5409410)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632896BDBM50632896(CHEMBL5434183)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandChemical structure of BindingDB Monomer ID 350262BDBM350262(US10208056, Compound 89)
Affinity DataIC50: 0.407nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248614BDBM50248614(CHEMBL4066819)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandChemical structure of BindingDB Monomer ID 350240BDBM350240(US10208056, Compound 67)
Affinity DataIC50: 0.466nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248635BDBM50248635(CHEMBL4070408)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632903BDBM50632903(CHEMBL5405004)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 350259BDBM350259(US10208056, Compound 86)
Affinity DataIC50: 0.480nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen). This is a kinase assay platform based on measuring the binding and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632905BDBM50632905(CHEMBL5414359)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241875BDBM50241875(CHEMBL4091527)
Affinity DataIC50: 0.540nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248633BDBM50248633(CHEMBL4083552)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248656BDBM50248656(CHEMBL4086487)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248656BDBM50248656(CHEMBL4086487)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248645BDBM50248645(CHEMBL4061525)
Affinity DataIC50: 0.590nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248640BDBM50248640(CHEMBL4074204)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632901BDBM50632901(CHEMBL5416117)
Affinity DataIC50: 0.630nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248690BDBM50248690(CHEMBL4082469)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265275BDBM50265275(4-(4-iodophenoxy)-2-(2H-tetrazol-5-yl)thieno[2,3-c...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632918BDBM50632918(CHEMBL5396725)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632907BDBM50632907(CHEMBL5402477)
Affinity DataIC50: 0.710nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50189434BDBM50189434(CHEMBL3828221)
Affinity DataIC50: 0.710nMAssay Description:Competitive binding affinity to full length His-tagged human recombinant CDK8/cyclin C expressed in baculovirus after 20 mins in presence of Alexa647...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2017
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 350253BDBM350253(US10208056, Compound 80)
Affinity DataIC50: 0.770nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen). This is a kinase assay platform based on measuring the binding and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248635BDBM50248635(CHEMBL4070408)
Affinity DataIC50: 0.770nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 350249BDBM350249(US10208056, Compound 76)
Affinity DataIC50: 0.827nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen). This is a kinase assay platform based on measuring the binding and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632904BDBM50632904(CHEMBL5411825)
Affinity DataIC50: 0.830nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632915BDBM50632915(CHEMBL5440319)
Affinity DataIC50: 0.880nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandChemical structure of BindingDB Monomer ID 640341BDBM640341(8-Amino-N-(cyclopropylmethyl)-5-(4- (1-(2-(dimethy...)
Affinity DataIC50: 0.880nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632898BDBM50632898(CHEMBL5416758)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50189415BDBM50189415(CHEMBL3828637)
Affinity DataIC50: 0.900nMAssay Description:Competitive binding affinity to full length His-tagged human recombinant CDK8/cyclin C expressed in baculovirus after 20 mins in presence of Alexa647...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50189415BDBM50189415(CHEMBL3828637)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of CDK8/Cyclin C (unknown origin) measured after 1 hr by plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248611BDBM50248611(CHEMBL4060856)
Affinity DataIC50: 0.930nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandChemical structure of BindingDB Monomer ID 640350BDBM640350(2-(4-(4-(8-amino-3-(azetidine-1- carbonyl)-1,7-nap...)
Affinity DataIC50: 0.960nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248611BDBM50248611(CHEMBL4060856)
Affinity DataIC50: 0.970nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248638BDBM50248638(CHEMBL4062244)
Affinity DataIC50: 0.990nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248614BDBM50248614(CHEMBL4066819)
Affinity DataIC50: 0.990nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50573483BDBM50573483(CHEMBL4877883 | US12410194, Compound 020)
Affinity DataIC50: 1nMAssay Description:Inhibition of tracer 236 binding to recombinant human His-tagged full length CDK8/Cyclin C expressed in baculovirus expression system by Lanthascreen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50573930BDBM50573930(CHEMBL4856177)
Affinity DataIC50: 1nMAssay Description:Inhibition of human CDK8/cyclin C incubated for 2 hrs by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandChemical structure of BindingDB Monomer ID 532287BDBM532287(US11213520, Example I-005)
Affinity DataIC50: 1nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50189428BDBM50189428(CHEMBL3828458)
Affinity DataIC50: 1nMAssay Description:Competitive binding affinity to full length His-tagged human recombinant CDK8/cyclin C expressed in baculovirus after 20 mins in presence of Alexa647...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169081BDBM50169081(CHEMBL3806220)
Affinity DataIC50: 1nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandChemical structure of BindingDB Monomer ID 540074BDBM540074(US11261184, Example I-021)
Affinity DataIC50: 1nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

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