Compile Data Set for Download or QSAR
Report error Found 2502 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 11B1, mitochondrial'
TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347718BDBM347718(4-[(Z)-1-(2-Benzyloxybenzoyl)-2- (dimethylamino)vi...)
Affinity DataEC50:  0.00100nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347679BDBM347679(US9790217, 5 | (E)-2-(4-Chlorophenoxy)-3- (dimethy...)
Affinity DataEC50:  0.00100nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347757BDBM347757(CHEM-US-00174 | US9790217, 79)
Affinity DataEC50:  0.00300nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347763BDBM347763(CHEM-US-00182 | US9790217, 85)
Affinity DataEC50:  0.00500nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347754BDBM347754(4-[[3-[2-(Pyridin-4-ylmethoxy)phenyl]-1H-pyrazol-4...)
Affinity DataEC50:  0.00700nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347758BDBM347758(CHEM-US-00175 | US9790217, 80)
Affinity DataEC50:  0.00700nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347755BDBM347755(CHEM-US-00172 | US9790217, 77)
Affinity DataEC50:  0.0110nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347756BDBM347756(CHEM-US-00173 | US9790217, 78)
Affinity DataEC50:  0.0110nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347679BDBM347679(US9790217, 5 | (E)-2-(4-Chlorophenoxy)-3- (dimethy...)
Affinity DataEC50:  0.0120nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347762BDBM347762(4-[[3-(2-Fluoro-3-hydroxyphenyl)-1H-pyrazol-4-yl]o...)
Affinity DataEC50:  0.0170nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347703BDBM347703((E)-1-[(2-Chlorobenzoyl)-2- (dimethylamino)vinylox...)
Affinity DataEC50:  0.0180nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347764BDBM347764(CHEM-US-00183 | US9790217, 86)
Affinity DataEC50:  0.0280nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347710BDBM347710(Methyl 3-[(E)-2-(4-cyanophenoxy)- 3-(dimethylamino...)
Affinity DataEC50:  0.0310nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347729BDBM347729(CHEM-US-00129 | US9790217, 52)
Affinity DataEC50:  0.0320nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347752BDBM347752(4-[[3-[3-[[3-Fluoro-3-(hydroxymethyl)azetidin-1-yl...)
Affinity DataEC50:  0.0360nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347745BDBM347745(CHEM-US-00162 | US9790217, 70)
Affinity DataEC50:  0.0380nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347731BDBM347731(CHEM-US-00131 | US9790217, 54)
Affinity DataEC50:  0.0460nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347744BDBM347744(4-[[3-[3-[(6-Fluoropyridin-2-yl)oxymethyl]phenyl]-...)
Affinity DataEC50:  0.0480nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 351275BDBM351275(US9796702, 36 | (rac)-6-[4-[1-(1-Acetylpiperidin-4...)
Affinity DataEC50:  0.0490nMAssay Description:The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347728BDBM347728(US9790217, 51)
Affinity DataEC50:  0.0510nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347727BDBM347727(4-[[3-[3-(Pyridin-2-ylmethoxy)phenyl]-1H-pyrazol-4...)
Affinity DataEC50:  0.0520nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347681BDBM347681((E)-2-(4-Chlorophenoxy)-1-(2- chlorophenyl)-3-(dim...)
Affinity DataEC50:  0.0520nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347713BDBM347713(4-[(Z)-1-(3-Benzyloxybenzoyl)-2- (dimethylamino)vi...)
Affinity DataEC50:  0.0530nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 351274BDBM351274(US9796702, 35 | (rac)-6-[4-[1-(1-Acetylpiperidin-4...)
Affinity DataEC50:  0.0670nMAssay Description:The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347712BDBM347712(4-[(Z)-1-(2-Chloro-3-fluoro- benzoyl)- (dimethylam...)
Affinity DataEC50:  0.0690nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 351277BDBM351277(US9796702, 38 | (+)-6-[4-[(1R)-1-(1-acetylpiperidi...)
Affinity DataEC50:  0.0740nMAssay Description:The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347685BDBM347685((E)-2-(4-Chlorophenoxy)-1-[2- (difluoromethoxy)phe...)
Affinity DataEC50:  0.0760nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 351263BDBM351263(US9796702, 26 | CHEM-US-00074 | US9796702, 24)
Affinity DataEC50:  0.0760nMAssay Description:The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347725BDBM347725(4-[[3-(3-Hydroxyphenyl)-1H-pyrazol-4-yl]oxy]benzon...)
Affinity DataEC50:  0.0830nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347726BDBM347726(4-[[3-[3-(Hydroxymethyl)phenyl]-1H-pyrazol-4-yl]ox...)
Affinity DataEC50:  0.0850nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347733BDBM347733(CHEM-US-00133 | US9790217, 56)
Affinity DataEC50:  0.0940nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 249226BDBM249226(US9458135, 14)
Affinity DataEC50:  0.100nMAssay Description:Herein we identified the use of the G-402 cell line as a host cell to ectopically express (transiently or stably) enzymes of the CYP11 family. Specif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347735BDBM347735(4-[[5-(3-Butoxyphenyl)-1H-pyrazol-4-yl]oxy]benzoni...)
Affinity DataEC50:  0.102nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 351261BDBM351261(US9796702, 22 | CHEM-US-00072)
Affinity DataEC50:  0.133nMAssay Description:The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347705BDBM347705(4-[(E)-1-(2-Chlorobenzoyl)-2- (dimethylamino)vinyl...)
Affinity DataEC50:  0.134nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347753BDBM347753(4-[[3-[3-(Morpholin-4-ylmethyl)phenyl]-1H-pyrazol-...)
Affinity DataEC50:  0.139nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347692BDBM347692((E)-2-(4-Chlorophenoxy)-1-(2,4- difluorophenyl)-3-...)
Affinity DataEC50:  0.159nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347724BDBM347724(CHEM-US-00117 | US9790217, 47)
Affinity DataEC50:  0.159nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347706BDBM347706((E)-1-[(2,3-Difluorobenzoyl)-2-(dimethylamino)viny...)
Affinity DataEC50:  0.161nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347686BDBM347686((E)-2-(4-Chlorophenoxy)-3- (dimethylamino)-1-(2-fl...)
Affinity DataEC50:  0.167nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347759BDBM347759(CHEM-US-00176 | US9790217, 81)
Affinity DataEC50:  0.171nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 351260BDBM351260(US9796702, 25 | 6-[4-[(1-Acetyl-4-piperidyl)methyl...)
Affinity DataEC50:  0.184nMAssay Description:The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347707BDBM347707(4-[(E)-1-(3-Chloro-2-fluoro- benzoyl)-2- (dimethyl...)
Affinity DataEC50:  0.191nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347730BDBM347730(CHEM-US-00130 | US9790217, 53)
Affinity DataEC50:  0.198nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 351278BDBM351278(US9796702, 39 | 5-Chloro-6-[4-[(2-ethylsulfonyl-2-...)
Affinity DataEC50:  0.215nMAssay Description:The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 351257BDBM351257(US9796702, 18 | 6-[4-[(1-Ethylsulfonyl-4-piperidyl...)
Affinity DataEC50:  0.216nMAssay Description:The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347711BDBM347711((E)-1-(2-Chloro-3-fluoro-phenyl)-2- (4-chloropheno...)
Affinity DataEC50:  0.262nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 351018BDBM351018(US9796702, 16 | 6-[4-[(1-Acetyl-4-piperidyl)methyl...)
Affinity DataEC50:  0.266nMAssay Description:The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347732BDBM347732(CHEM-US-00132 | US9790217, 55)
Affinity DataEC50:  0.288nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 50444550BDBM50444550(CHEMBL3099704)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
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