Report error Found 181 Enz. Inhib. hit(s) with Target = 'Cytochrome c oxidase subunit 1'
Affinity DataIC50: 7.90nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of COX-1 in human whole blood assessed as reduction in thromboxane B2 production by immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 321nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 5...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant COX-1 using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Affinity DataIC50: 950nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 5...More data for this Ligand-Target Pair
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 5...More data for this Ligand-Target Pair
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 5...More data for this Ligand-Target Pair
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of human recombinant COX-1 using [1-14C] arachidonic acid as substrate preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 3.08E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Affinity DataIC50: 5.73E+3nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 5...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of ovine COX1 preincubated for 5 mins followed by arachidonic acid addition and measured after 2 mins by colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of ovine COX1 preincubated for 5 mins followed by arachidonic acid addition and measured after 2 mins by colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Affinity DataIC50: 7.27E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 7.49E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 7.64E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 8.51E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 8.73E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:H9C2 cells were incubated in DMEM (Hyclone, GE LifeSciences) with 10% FBS (Gibco, Life Technologies) and 1 Glutamine (Gibco, Life Technologies) and N...More data for this Ligand-Target Pair
