Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with Target = 'DNA repair protein RAD52 homolog'
TargetDNA repair protein RAD52 homolog(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50070942BDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 277nMAssay Description:Inhibition of 6His-tagged human RD52 assessed as reduction in RD52 binding to Cy3-dT30-Cy5 ssDNA incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetDNA repair protein RAD52 homolog(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436204BDBM50436204(CHEMBL109037)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetDNA repair protein RAD52 homolog(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565810BDBM50565810(Strictinin)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of 6His-tagged human RD52 assessed as reduction in RD52 binding to Cy3-dT30-Cy5 ssDNA incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetDNA repair protein RAD52 homolog(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187665BDBM50187665((-)-epigallocatechin | CHEMBL47386)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of 6His-tagged human RD52 assessed as reduction in RD52 binding to Cy3-dT30-Cy5 ssDNA incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetDNA repair protein RAD52 homolog(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635711BDBM50635711(CHEMBL5559362)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of RAD52 (unknown origin) by FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA repair protein RAD52 homolog(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635710BDBM50635710(CHEMBL5542154)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of RAD52 (unknown origin) by FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA repair protein RAD52 homolog(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60996BDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetDNA repair protein RAD52 homolog(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565802BDBM50565802(CHEMBL4165444 | US11584714, Compound 29)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetDNA repair protein RAD52 homolog(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565803BDBM50565803(CHEMBL4777728)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetDNA repair protein RAD52 homolog(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565804BDBM50565804(CHEMBL4796552)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetDNA repair protein RAD52 homolog(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565805BDBM50565805(CHEMBL4785153)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetDNA repair protein RAD52 homolog(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565806BDBM50565806(CHEMBL4795092)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetDNA repair protein RAD52 homolog(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565807BDBM50565807(CHEMBL4785174)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetDNA repair protein RAD52 homolog(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565808BDBM50565808(CHEMBL4785369)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetDNA repair protein RAD52 homolog(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23223BDBM23223(Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetDNA repair protein RAD52 homolog(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565809BDBM50565809(CHEMBL1718911)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human RAD52 assessed as reduction in DNA annealing using tailed ds-DNA 337-F/1337-BHQ1 by fluorescence-quenching assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetDNA repair protein RAD52 homolog(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565809BDBM50565809(CHEMBL1718911)
Affinity DataKd:  2.58E+4nMAssay Description:Binding affinity to RAD52 (unknown origin) assessed as dissociation constant by Surface Plasmon ResonanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed